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Gastrobiotic 550mg 20 Tablets

EGP344

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Medication Name: Gastrobiotic 550 mg Tablets (20 Tablets)
Active Ingredient: Rifaximin 550 mg

Pharmacologic Class: Non-systemic (gut-targeted) antibiotic – rifamycin derivative


Indications:

  • Traveler’s diarrhea caused by non-invasive Escherichia coli

  • Irritable bowel syndrome with diarrhea (IBS-D)

  • Hepatic encephalopathy (to reduce recurrence of episodes)

  • Bacterial overgrowth or intestinal infections due to susceptible organisms


Dosage and Administration:
Adults:

  • Traveler’s diarrhea: 200 mg every 8 hours for 3 days

  • IBS-D: 550 mg every 8 hours for 14 days

  • Hepatic encephalopathy: 550 mg every 12 hours (continuous treatment)

  • Take orally with or without food.

  • Swallow the tablet whole with water.

  • Follow physician instructions strictly.


Contraindications:

  • Hypersensitivity to rifaximin, rifamycin derivatives, or any component of the formulation

  • Severe diarrhea with blood or high fever (possible invasive bacterial infection)

  • Caution in patients with severe hepatic impairment (Child-Pugh C)


Precautions:

  • Use with caution in liver disease; plasma concentrations may increase.

  • Not recommended for systemic infections because absorption from the gut is minimal.

  • Avoid unnecessary use to prevent bacterial resistance.

  • Safety in pregnancy and breastfeeding not well established — use only if clearly needed.


Common Side Effects:

  • Nausea, flatulence, abdominal pain or bloating

  • Headache or dizziness

  • Constipation or diarrhea

  • Fatigue

Serious Side Effects (rare):

  • Hypersensitivity reactions (rash, urticaria, facial swelling)

  • Severe diarrhea due to Clostridium difficile (rare)


Storage Conditions:

  • Store below 25°C, protected from light and moisture.

  • Keep out of reach of children.

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