Teklo 30 Tablets

Teklo (30 Tablets)

Active Ingredients:

• Atenolol 100 mg

• Chlorthalidone 25 mg

• Amiloride hydrochloride 5 mg

Therapeutic Class:
Combination Antihypertensive – Beta-blocker + Thiazide-like Diuretic + Potassium-sparing Diuretic

Indications:

• Essential Hypertension (High Blood Pressure) – especially when monotherapy is not sufficient.

• May also be useful in patients with mild fluid retention where a diuretic effect is beneficial.

Dosage:

• Usual adult dose: One tablet once daily, preferably in the morning to reduce nighttime urination.

• May be taken with or without food.

• Dose adjustments should be made according to clinical response and blood pressure control.

Mechanism of Action:

• Atenolol: Selective beta₁-blocker that lowers heart rate, cardiac output, and blood pressure.

• Chlorthalidone: Thiazide-like diuretic that increases sodium and water excretion, reducing blood volume.

• Amiloride: Potassium-sparing diuretic that prevents potassium loss caused by other diuretics.
  → The combination provides effective blood pressure reduction while minimizing potassium loss.

Precautions:

• Contraindicated in:

  • Severe bradycardia or heart block

  • Cardiogenic shock or severe hypotension

  • Anuria or severe renal impairment

  • Hypersensitivity to any component

• Use with caution in:

  • Diabetes mellitus (beta-blocker may mask hypoglycemia symptoms)

  • Asthma or COPD (risk of bronchospasm)

  • Gout (chlorthalidone may raise uric acid levels)

  • Electrolyte disturbances (monitor potassium and sodium)

  • Renal or hepatic impairment

• Avoid abrupt withdrawal of atenolol to prevent rebound hypertension or angina.

Possible Side Effects:

• Fatigue, dizziness, or lightheadedness

• Bradycardia (slow pulse)

• Cold extremities

• Hypotension

• Increased urination or dehydration

• Electrolyte imbalances (low sodium or altered potassium)

• Elevated uric acid or glucose levels

• Rare: rash, nausea, or muscle cramps

Storage:
Store below 30°C in a dry place, away from direct sunlight and moisture.
Keep out of reach of children.