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Cycloprogeneva 21 tab

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Medication Name: Cyclo-Progynova 21 tablets
Active Ingredients:

  • Estradiol valerate 2 mg (estrogen)

  • Norgestrel 0.5 mg (progestogen)

Drug Class: Hormone replacement therapy (HRT) and cycle regulator


Indications:

Cyclo-Progynova is primarily used for:

  1. Hormone replacement therapy (HRT) in women with symptoms due to estrogen deficiency (especially during or after menopause), such as:

    • Hot flashes and night sweats

    • Vaginal dryness or discomfort

    • Mood swings or sleep disturbances

  2. Cycle regulation in women with irregular menstrual cycles caused by hormonal imbalance.

  3. Sometimes prescribed after certain gynecological treatments to restore a normal cycle pattern.


Dosage and Administration:

  • The pack contains 21 tablets with two types of tablets:

    • White tablets (Estradiol only): usually taken for the first 11 days.

    • Light brown tablets (Estradiol + Norgestrel): taken for the following 10 days.

  • Take one tablet daily at the same time each day for 21 consecutive days, followed by a 7-day tablet-free break, during which a withdrawal bleed (similar to a period) usually occurs.

  • After the 7-day break, start the next pack regardless of whether bleeding has stopped.


Side Effects:

  • Breast tenderness or swelling

  • Nausea, bloating

  • Headache or mild migraine

  • Mood changes

  • Spotting or breakthrough bleeding

  • Fluid retention

  • Rare: blood clots (deep vein thrombosis, pulmonary embolism), especially in smokers or women over 35


Warnings and Precautions:

  • Not suitable for women with:

    • Breast or estrogen-dependent cancer

    • Unexplained vaginal bleeding

    • Active liver disease

    • History of blood clots or stroke

  • Use cautiously if you have hypertension, diabetes, migraine, or gallbladder issues.

  • Requires periodic medical follow-up and breast exams.


Storage:

Store below 25°C, away from light and moisture.

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