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Dapsone 100mg 20 Tablets

EGP158

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Medication Name: Dapsone 100 mg Tablets (20 Tablets)
Active Ingredient: Dapsone 100 mg

Pharmacologic Class: Sulfone antibiotic and anti-inflammatory agent


Indications:

  • Treatment of leprosy (Hansen’s disease), usually in combination with other antileprosy drugs.

  • Dermatitis herpetiformis (chronic blistering skin condition associated with celiac disease).

  • Certain cases of acne and other chronic skin infections caused by susceptible organisms.

  • Prophylaxis and treatment of Pneumocystis jirovecii pneumonia in immunocompromised patients (e.g., HIV).


Dosage and Administration:

  • Usual adult dose: 50–100 mg once daily, depending on the condition and patient response.

  • Take orally with or after food to minimize stomach upset.

  • Follow the prescribed dose schedule carefully; do not stop abruptly without medical advice.


Contraindications:

  • Known hypersensitivity to dapsone or other sulfone drugs.

  • Severe anemia or significant blood disorders.

  • Severe liver disease.


Precautions:

  • Monitor blood counts regularly; dapsone may cause hemolysis (especially in patients with G6PD deficiency).

  • Use cautiously in patients with liver or kidney impairment.

  • May cause methemoglobinemia (reduced oxygen-carrying capacity of blood).

  • Inform the physician if symptoms such as fatigue, shortness of breath, or bluish skin appear.


Common Side Effects:

  • Nausea, vomiting, or loss of appetite

  • Headache

  • Skin rash or itching

  • Mild anemia

Serious Side Effects (rare):

  • Hemolytic anemia or methemoglobinemia (signs: fatigue, pallor, cyanosis)

  • Peripheral neuropathy (tingling or numbness in hands or feet)

  • Severe allergic skin reactions (Stevens-Johnson syndrome)

  • Liver dysfunction (yellowing of skin or eyes, dark urine)


Storage Conditions:

  • Store below 25°C in a dry place, away from moisture and direct sunlight.

  • Keep out of reach of children.

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