Epicephin 1000mg IM Vial

Indications:
Used for the treatment of various bacterial infections such as:

• Respiratory tract infections (bronchitis, pneumonia)

• Urinary tract infections

• Skin and soft tissue infections

• Bone and joint infections

• Abdominal infections

• Gonorrhea

• Meningitis

• Septicemia and other systemic infections

Mechanism of Action:
Ceftriaxone inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), resulting in disruption of cell wall formation and bacterial death.

Dosage:

• Adults: 500 mg to 1 g once daily, or divided every 12 hours depending on infection type and severity.

• Children: 50–75 mg/kg/day (maximum 2 g/day).

• Administered intramuscularly (IM) or intravenously (IV) as prescribed.

• For IM use, reconstitute the vial with sterile water or 1% lidocaine solution to reduce injection discomfort.

Precautions:

• Contraindicated in patients with cephalosporin hypersensitivity.

• Use with caution in those allergic to penicillins.

• Dose adjustments may be necessary in renal or hepatic impairment.

• Avoid co-administration with calcium-containing IV solutions, particularly in neonates.

Possible Side Effects:

• Pain or irritation at the injection site

• Nausea, vomiting, or diarrhea

• Skin rash or itching

• Headache or dizziness

• Rarely: Allergic reactions, colitis, or hematologic abnormalities