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Targofloxacin 750mg 10 Tablets

EGP188

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Medication Name: Targofloxacin 750mg 10 Tablets

Active Ingredient:
Tosufloxacin 750mg (a fluoroquinolone antibiotic)

Pharmacological Class:
Fluoroquinolone antibacterial agent

Indications:
Used to treat bacterial infections such as:

  • Respiratory tract infections (e.g., bronchitis, pneumonia)

  • Urinary tract infections

  • Skin and soft tissue infections

  • ENT infections (e.g., sinusitis, otitis media)

  • Gastrointestinal and genitourinary infections

Mechanism of Action:
Tosufloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, and repair, leading to bacterial death.

Dosage:

  • Typical adult dose: 750mg once daily, with or without food.

  • Duration of treatment depends on infection type, usually 5–14 days, as directed by a physician.

  • Should be taken with plenty of water and not skipped or stopped early.

Precautions:

  • Avoid in pregnancy, breastfeeding, and children under 18 years due to risk of cartilage damage.

  • Use cautiously in patients with renal or hepatic impairment.

  • Avoid exposure to direct sunlight (photosensitivity risk).

  • Do not take with antacids or iron/zinc supplements within 2 hours of the dose (reduces absorption).

  • May cause tendon inflammation or rupture, especially in elderly or those on corticosteroids.

  • Avoid driving or operating machinery if dizziness or blurred vision occurs.

Possible Side Effects:

  • Nausea, diarrhea, abdominal pain

  • Dizziness, headache, or insomnia

  • Skin rash or photosensitivity

  • Rare: tendonitis or tendon rupture

  • Rare: QT prolongation or hepatic enzyme elevation

  • Very rare: allergic reactions or central nervous system effects such as confusion or agitation

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