Mounjaro 7.5mg\0.6ml 1 Kwikpen

Mounjaro 7.5 mg/0.6 ml (1 KwikPen)

Active Ingredient:

• Tirzepatide 7.5 mg per 0.6 ml prefilled pen

Therapeutic Class:
Dual GIP and GLP-1 receptor agonist (antidiabetic and weight management agent)

Indications:

• Type 2 diabetes mellitus in adults to improve glycemic control:

  • As monotherapy when metformin is not tolerated or contraindicated.

  • In combination with other antidiabetic agents such as metformin, SGLT2 inhibitors, or insulin.

• May also be used off-label under specialist supervision for weight reduction in overweight or obese adults.

Dosage and Administration:

• Administer once weekly via subcutaneous injection in the abdomen, thigh, or upper arm.

• May be given at any time of day, with or without food.

• Rotate injection sites weekly to prevent skin irritation.

• If a dose is missed, it can be given within 4 days (96 hours); otherwise, skip and take the next dose as scheduled.

• The 7.5 mg dose is an intermediate step in dose escalation (usual sequence: 2.5 → 5 → 7.5 → 10 → 12.5 → 15 mg).

Mechanism of Action:

• Tirzepatide acts as a dual agonist at GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors.

• Enhances insulin secretion and suppresses glucagon in a glucose-dependent manner.

• Delays gastric emptying, reduces appetite, and promotes satiety.

• Results in better glycemic control and significant weight loss.

Precautions:

• Contraindicated in:

  • Personal or family history of medullary thyroid carcinoma (MTC)

  • Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

  • Severe gastrointestinal disease

• Use cautiously in patients with:

  • Pancreatitis history

  • Renal impairment, especially if experiencing dehydration from vomiting or diarrhea

• Not for type 1 diabetes or diabetic ketoacidosis.

• Monitor for hypoglycemia when combined with insulin or sulfonylureas.

Possible Side Effects:

• Nausea, vomiting, diarrhea, constipation (most common, often temporary)

• Loss of appetite, abdominal discomfort, fatigue

• Hypoglycemia (mainly when used with other antidiabetics)

• Rare: Pancreatitis, gallstones, allergic skin reactions

Storage:

• Store refrigerated (2–8°C).

• May be kept at room temperature (below 30°C) for up to 21 days.

• Do not freeze.

• Keep protected from light and out of reach of children.