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Epilat Retard 20mg 20 Tablets

EGP22

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Epilat Retard 20 mg (20 Tablets)

Active Ingredient:

  • Nifedipine 20 mg (Retard formulation) – Calcium channel blocker

Therapeutic Class:
Antihypertensive and antianginal agent

Indications:

  • Essential hypertension (high blood pressure)

  • Chronic stable angina pectoris

  • Vasospastic (Prinzmetal’s) angina

Dosage and Administration:

  • Typical dose: 1 tablet (20 mg) once or twice daily, depending on clinical response.

  • Tablets should be swallowed whole with water, preferably after meals.

  • Do not crush, chew, or break the tablet (retard form ensures slow release).

  • Dosage may be adjusted by the physician according to blood pressure and tolerance.

Mechanism of Action:

  • Nifedipine blocks calcium influx into vascular smooth muscle and cardiac cells.

  • Causes vasodilation of peripheral and coronary arteries.

  • Reduces systemic vascular resistance, blood pressure, and cardiac workload.

  • Improves oxygen delivery to myocardial tissue by dilating coronary vessels.

Precautions:

  • Contraindicated in:

    • Severe hypotension

    • Cardiogenic shock

    • Recent myocardial infarction (use with caution)

  • Use with caution in:

    • Heart failure, aortic stenosis, or hepatic impairment

  • Avoid grapefruit juice (may increase nifedipine levels).

  • Monitor blood pressure regularly during therapy.

Possible Side Effects:

  • Headache, flushing, dizziness

  • Peripheral edema (especially ankles)

  • Palpitations or tachycardia

  • Fatigue, nausea, or mild constipation

  • Rare: Gingival hyperplasia with long-term use

Storage:

  • Store below 25°C, in a dry place away from light and moisture.

  • Keep out of reach of children.

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