Nevilob Amlo 5\5mg 30 Tablets

Medication Name: Nevilob Amlo 5/5mg 30 Tablets

Active Ingredients (per tablet):

• Bisoprolol fumarate 5 mg

• Amlodipine besylate equivalent to Amlodipine 5 mg

Pharmacological Class:
Combination of a beta-blocker (Bisoprolol) and a calcium channel blocker (Amlodipine) — Antihypertensive

Dosage Form:
Film-coated tablets — 30 tablets per pack

Indications:

• Treatment of essential hypertension in patients whose blood pressure is not adequately controlled by monotherapy

• May also help reduce the risk of cardiovascular complications in patients with both hypertension and angina

Mechanism of Action:

• Bisoprolol: Selective β1-adrenergic receptor blocker that reduces heart rate, cardiac output, and renin release.

• Amlodipine: Inhibits calcium influx in vascular smooth muscle, causing vasodilation and lowering peripheral vascular resistance.
  The combined effect leads to effective blood pressure reduction and improved cardiac workload balance.

Dosage:

• Usual adult dose: One tablet once daily, preferably at the same time each day

• Can be taken with or without food

• Dose adjustments should be made based on clinical response

Precautions:

• Avoid in patients with severe bradycardia, heart block, or decompensated heart failure

• Use cautiously in hepatic impairment or hypotension

• Do not discontinue abruptly; taper gradually under medical supervision

Common Side Effects:

• Fatigue, dizziness, or headache

• Bradycardia

• Peripheral edema

• Flushing

• Gastrointestinal discomfort