{"id":4710,"date":"2025-11-05T11:45:41","date_gmt":"2025-11-05T11:45:41","guid":{"rendered":"https:\/\/nawarpharmacy.com\/?post_type=product&#038;p=4710"},"modified":"2025-11-07T12:54:03","modified_gmt":"2025-11-07T12:54:03","slug":"co-tareg-16012-5mg-28-tablets","status":"publish","type":"product","link":"https:\/\/nawarpharmacy.com\/ru\/product\/co-tareg-16012-5mg-28-tablets\/","title":{"rendered":"Co-Tareg 160\\12.5mg 28 Tablets"},"content":{"rendered":"<article class=\"text-token-text-primary w-full focus:outline-none [--shadow-height:45px] has-data-writing-block:pointer-events-none has-data-writing-block:-mt-(--shadow-height) has-data-writing-block:pt-(--shadow-height) [&amp;:has([data-writing-block])&gt;*]:pointer-events-auto [content-visibility:auto] supports-[content-visibility:auto]:[contain-intrinsic-size:auto_100lvh] scroll-mt-[calc(var(--header-height)+min(200px,max(70px,20svh)))]\" dir=\"auto\" data-turn-id=\"f4ba56f6-cf49-4b37-8f99-e973186f6a8c\" data-testid=\"conversation-turn-663\" data-scroll-anchor=\"true\" data-turn=\"assistant\">\n<div class=\"text-base my-auto mx-auto pb-10 [--thread-content-margin:--spacing(4)] thread-sm:[--thread-content-margin:--spacing(6)] thread-lg:[--thread-content-margin:--spacing(16)] px-(--thread-content-margin)\">\n<div class=\"[--thread-content-max-width:40rem] thread-lg:[--thread-content-max-width:48rem] mx-auto max-w-(--thread-content-max-width) flex-1 group\/turn-messages focus-visible:outline-hidden relative flex w-full min-w-0 flex-col agent-turn\">\n<div class=\"flex max-w-full flex-col grow\">\n<div class=\"min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal [.text-message+&amp;]:mt-1\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"f4ba56f6-cf49-4b37-8f99-e973186f6a8c\" data-message-model-slug=\"gpt-5\">\n<div class=\"flex w-full flex-col gap-1 empty:hidden first:pt-[1px]\">\n<div class=\"markdown prose dark:prose-invert w-full break-words light markdown-new-styling\">\n<p data-start=\"0\" data-end=\"53\"><strong data-start=\"0\" data-end=\"20\">Medication Name:<\/strong> Co-Tareg 160\/12.5mg 28 Tablets<\/p>\n<p data-start=\"55\" data-end=\"93\"><strong data-start=\"55\" data-end=\"91\">Active Ingredients (per tablet):<\/strong><\/p>\n<ul data-start=\"94\" data-end=\"146\">\n<li data-start=\"94\" data-end=\"114\">\n<p data-start=\"96\" data-end=\"114\">Valsartan 160 mg<\/p>\n<\/li>\n<li data-start=\"115\" data-end=\"146\">\n<p data-start=\"117\" data-end=\"146\">Hydrochlorothiazide 12.5 mg<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"148\" data-end=\"176\"><strong data-start=\"148\" data-end=\"174\">Pharmacological Class:<\/strong><\/p>\n<ul data-start=\"177\" data-end=\"272\">\n<li data-start=\"177\" data-end=\"229\">\n<p data-start=\"179\" data-end=\"229\">Valsartan: Angiotensin II receptor blocker (ARB)<\/p>\n<\/li>\n<li data-start=\"230\" data-end=\"272\">\n<p data-start=\"232\" data-end=\"272\">Hydrochlorothiazide: Thiazide diuretic<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"274\" data-end=\"316\"><strong data-start=\"274\" data-end=\"290\">Dosage Form:<\/strong><br data-start=\"290\" data-end=\"293\" \/>Tablets \u2014 28 per pack<\/p>\n<p data-start=\"318\" data-end=\"336\"><strong data-start=\"318\" data-end=\"334\">Indications:<\/strong><\/p>\n<ul data-start=\"337\" data-end=\"605\">\n<li data-start=\"337\" data-end=\"480\">\n<p data-start=\"339\" data-end=\"480\">Treatment of <strong data-start=\"352\" data-end=\"400\">essential hypertension (high blood pressure)<\/strong> in patients whose blood pressure is not adequately controlled by monotherapy.<\/p>\n<\/li>\n<li data-start=\"481\" data-end=\"605\">\n<p data-start=\"483\" data-end=\"605\">May be used as <strong data-start=\"498\" data-end=\"522\">substitution therapy<\/strong> for patients already stabilized on valsartan and hydrochlorothiazide separately.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"607\" data-end=\"633\"><strong data-start=\"607\" data-end=\"631\">Mechanism of Action:<\/strong><\/p>\n<ul data-start=\"634\" data-end=\"1079\">\n<li data-start=\"634\" data-end=\"806\">\n<p data-start=\"636\" data-end=\"806\"><strong data-start=\"636\" data-end=\"650\">Valsartan:<\/strong> Blocks the effects of angiotensin II at the AT1 receptor, preventing vasoconstriction and aldosterone secretion, which leads to decreased blood pressure.<\/p>\n<\/li>\n<li data-start=\"807\" data-end=\"978\">\n<p data-start=\"809\" data-end=\"978\"><strong data-start=\"809\" data-end=\"833\">Hydrochlorothiazide:<\/strong> Increases sodium and water excretion by inhibiting sodium reabsorption in the distal renal tubules, reducing plasma volume and blood pressure.<\/p>\n<\/li>\n<li data-start=\"979\" data-end=\"1079\">\n<p data-start=\"981\" data-end=\"1079\">The combination provides <strong data-start=\"1006\" data-end=\"1043\">additive antihypertensive effects<\/strong> through complementary mechanisms.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1081\" data-end=\"1094\"><strong data-start=\"1081\" data-end=\"1092\">Dosage:<\/strong><\/p>\n<ul data-start=\"1095\" data-end=\"1249\">\n<li data-start=\"1095\" data-end=\"1165\">\n<p data-start=\"1097\" data-end=\"1165\">Usual dose: <strong data-start=\"1109\" data-end=\"1134\">One tablet once daily<\/strong>, taken with or without food.<\/p>\n<\/li>\n<li data-start=\"1166\" data-end=\"1249\">\n<p data-start=\"1168\" data-end=\"1249\">Dosage may be adjusted based on blood pressure response and clinical condition.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1251\" data-end=\"1269\"><strong data-start=\"1251\" data-end=\"1267\">Precautions:<\/strong><\/p>\n<ul data-start=\"1270\" data-end=\"1680\">\n<li data-start=\"1270\" data-end=\"1385\">\n<p data-start=\"1272\" data-end=\"1385\">Monitor <strong data-start=\"1280\" data-end=\"1372\">renal function, serum electrolytes (especially potassium and sodium), and blood pressure<\/strong> regularly.<\/p>\n<\/li>\n<li data-start=\"1386\" data-end=\"1481\">\n<p data-start=\"1388\" data-end=\"1481\">Use with caution in patients with <strong data-start=\"1422\" data-end=\"1478\">renal impairment, hepatic disease, diabetes, or gout<\/strong>.<\/p>\n<\/li>\n<li data-start=\"1482\" data-end=\"1575\">\n<p data-start=\"1484\" data-end=\"1575\">Contraindicated in <strong data-start=\"1503\" data-end=\"1516\">pregnancy<\/strong>, <strong data-start=\"1518\" data-end=\"1556\">severe renal or hepatic impairment<\/strong>, and <strong data-start=\"1562\" data-end=\"1572\">anuria<\/strong>.<\/p>\n<\/li>\n<li data-start=\"1576\" data-end=\"1680\">\n<p data-start=\"1578\" data-end=\"1680\">Avoid combining with <strong data-start=\"1599\" data-end=\"1624\">potassium supplements<\/strong> or <strong data-start=\"1628\" data-end=\"1659\">potassium-sparing diuretics<\/strong> unless prescribed.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1682\" data-end=\"1708\"><strong data-start=\"1682\" data-end=\"1706\">Common Side Effects:<\/strong><\/p>\n<ul data-start=\"1709\" data-end=\"1893\">\n<li data-start=\"1709\" data-end=\"1741\">\n<p data-start=\"1711\" data-end=\"1741\">Dizziness or lightheadedness<\/p>\n<\/li>\n<li data-start=\"1742\" data-end=\"1753\">\n<p data-start=\"1744\" data-end=\"1753\">Fatigue<\/p>\n<\/li>\n<li data-start=\"1754\" data-end=\"1769\">\n<p data-start=\"1756\" data-end=\"1769\">Hypotension<\/p>\n<\/li>\n<li data-start=\"1770\" data-end=\"1793\">\n<p data-start=\"1772\" data-end=\"1793\">Increased urination<\/p>\n<\/li>\n<li data-start=\"1794\" data-end=\"1825\">\n<p data-start=\"1796\" data-end=\"1825\">Hypokalemia or hyponatremia<\/p>\n<\/li>\n<li data-start=\"1826\" data-end=\"1863\">\n<p data-start=\"1828\" data-end=\"1863\">Elevated blood urea or creatinine<\/p>\n<\/li>\n<li data-start=\"1864\" data-end=\"1893\">\n<p data-start=\"1866\" data-end=\"1893\">Muscle cramps or weakness<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1895\" data-end=\"2163\" data-is-last-node=\"\" data-is-only-node=\"\"><strong data-start=\"1895\" data-end=\"1904\">Note:<\/strong><br data-start=\"1904\" data-end=\"1907\" \/>Co-Tareg 160\/12.5mg is an effective once-daily combination therapy that offers enhanced blood pressure control through dual action \u2014 <strong data-start=\"2040\" data-end=\"2067\">blocking angiotensin II<\/strong> and <strong data-start=\"2072\" data-end=\"2099\">promoting mild diuresis<\/strong>, thereby reducing cardiovascular risk in hypertensive patients.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"z-0 flex min-h-[46px] justify-start\"><\/div>\n<\/div>\n<\/div>\n<\/article>\n<div class=\"pointer-events-none h-px w-px\" aria-hidden=\"true\" data-edge=\"true\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Medication Name: Co-Tareg 160\/12.5mg 28 Tablets Active Ingredients (per tablet): Valsartan 160 mg Hydrochlorothiazide 12.5 mg Pharmacological Class: Valsartan: Angiotensin II receptor blocker (ARB) Hydrochlorothiazide: Thiazide diuretic Dosage Form:Tablets \u2014 28 per pack Indications: Treatment of essential hypertension (high blood pressure) in patients whose blood pressure is not adequately controlled by monotherapy. May be used&#8230;<\/p>\n","protected":false},"featured_media":4873,"comment_status":"open","ping_status":"closed","template":"","meta":{"rs_blank_template":"","rs_page_bg_color":"","slide_template_v7":"","_bst_post_transparent":"default","_bst_post_title":"","_bst_post_layout":"default","_bst_post_sidebar_id":"","_bst_post_content_style":"default","_bst_post_vertical_padding":"default","_bst_post_feature":"","_bst_post_feature_position":"","_bst_post_header":false,"_bst_post_footer":false},"product_brand":[],"product_cat":[80,45],"product_tag":[],"product_brands":[],"class_list":{"0":"post-4710","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-cardiovascular-blood-pressure","7":"product_cat-medicines","9":"first","10":"instock","11":"shipping-taxable","12":"purchasable","13":"product-type-simple","14":"entry","15":"content-bg","16":"loop-entry"},"_links":{"self":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product\/4710","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/comments?post=4710"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/media\/4873"}],"wp:attachment":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/media?parent=4710"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_brand?post=4710"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_cat?post=4710"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_tag?post=4710"},{"taxonomy":"product_brands","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_brands?post=4710"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}