{"id":4010,"date":"2025-10-24T08:21:47","date_gmt":"2025-10-24T08:21:47","guid":{"rendered":"https:\/\/nawarpharmacy.com\/?post_type=product&#038;p=4010"},"modified":"2025-10-25T13:13:30","modified_gmt":"2025-10-25T13:13:30","slug":"ezapril-co-2012-5mg-30-tablets","status":"publish","type":"product","link":"https:\/\/nawarpharmacy.com\/ru\/product\/ezapril-co-2012-5mg-30-tablets\/","title":{"rendered":"Ezapril Co 20\\12.5mg 30 Tablets"},"content":{"rendered":"<article class=\"text-token-text-primary w-full focus:outline-none [--shadow-height:45px] has-data-writing-block:pointer-events-none has-data-writing-block:-mt-(--shadow-height) has-data-writing-block:pt-(--shadow-height) [&amp;:has([data-writing-block])&gt;*]:pointer-events-auto [content-visibility:auto] supports-[content-visibility:auto]:[contain-intrinsic-size:auto_100lvh] scroll-mt-[calc(var(--header-height)+min(200px,max(70px,20svh)))]\" dir=\"auto\" data-turn-id=\"request-68f645cb-9280-8327-a300-008dc440122c-6\" data-testid=\"conversation-turn-165\" data-scroll-anchor=\"true\" data-turn=\"assistant\">\n<div class=\"text-base my-auto mx-auto pb-10 [--thread-content-margin:--spacing(4)] thread-sm:[--thread-content-margin:--spacing(6)] thread-lg:[--thread-content-margin:--spacing(16)] px-(--thread-content-margin)\">\n<div class=\"[--thread-content-max-width:40rem] thread-lg:[--thread-content-max-width:48rem] mx-auto max-w-(--thread-content-max-width) flex-1 group\/turn-messages focus-visible:outline-hidden relative flex w-full min-w-0 flex-col agent-turn\">\n<div class=\"flex max-w-full flex-col grow\">\n<div class=\"min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal [.text-message+&amp;]:mt-1\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"7252dbda-544d-4d44-83ae-82f9edbd359b\" data-message-model-slug=\"gpt-5-mini\">\n<div class=\"flex w-full flex-col gap-1 empty:hidden first:pt-[1px]\">\n<div class=\"markdown prose dark:prose-invert w-full break-words light markdown-new-styling\">\n<p data-start=\"0\" data-end=\"40\"><strong data-start=\"0\" data-end=\"38\">Ezapril Co 20\/12.5 mg (30 Tablets)<\/strong><\/p>\n<p data-start=\"42\" data-end=\"67\"><strong data-start=\"42\" data-end=\"65\">Active Ingredients:<\/strong><\/p>\n<ul data-start=\"68\" data-end=\"155\">\n<li data-start=\"68\" data-end=\"103\">\n<p data-start=\"70\" data-end=\"103\">Enalapril 20 mg (ACE inhibitor)<\/p>\n<\/li>\n<li data-start=\"104\" data-end=\"155\">\n<p data-start=\"106\" data-end=\"155\">Hydrochlorothiazide 12.5 mg (Thiazide diuretic)<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"157\" data-end=\"248\"><strong data-start=\"157\" data-end=\"179\">Therapeutic Class:<\/strong><br data-start=\"179\" data-end=\"182\" \/>Combination antihypertensive \u2013 ACE inhibitor + Thiazide diuretic<\/p>\n<p data-start=\"250\" data-end=\"268\"><strong data-start=\"250\" data-end=\"266\">Indications:<\/strong><\/p>\n<ul data-start=\"269\" data-end=\"453\">\n<li data-start=\"269\" data-end=\"367\">\n<p data-start=\"271\" data-end=\"367\"><strong data-start=\"271\" data-end=\"309\">Hypertension (high blood pressure)<\/strong> in adults, especially when monotherapy is insufficient.<\/p>\n<\/li>\n<li data-start=\"368\" data-end=\"453\">\n<p data-start=\"370\" data-end=\"453\">May be used to reduce <strong data-start=\"392\" data-end=\"415\">cardiovascular risk<\/strong> in patients requiring dual therapy.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"455\" data-end=\"468\"><strong data-start=\"455\" data-end=\"466\">Dosage:<\/strong><\/p>\n<ul data-start=\"469\" data-end=\"703\">\n<li data-start=\"469\" data-end=\"544\">\n<p data-start=\"471\" data-end=\"544\"><strong data-start=\"471\" data-end=\"492\">Usual adult dose:<\/strong> One tablet once daily, preferably in the morning.<\/p>\n<\/li>\n<li data-start=\"545\" data-end=\"587\">\n<p data-start=\"547\" data-end=\"587\">Can be taken <strong data-start=\"560\" data-end=\"584\">with or without food<\/strong>.<\/p>\n<\/li>\n<li data-start=\"588\" data-end=\"703\">\n<p data-start=\"590\" data-end=\"703\">Dose adjustments may be required based on <strong data-start=\"632\" data-end=\"700\">blood pressure response, kidney function, and electrolyte levels<\/strong>.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"705\" data-end=\"731\"><strong data-start=\"705\" data-end=\"729\">Mechanism of Action:<\/strong><\/p>\n<ul data-start=\"732\" data-end=\"1148\">\n<li data-start=\"732\" data-end=\"919\">\n<p data-start=\"734\" data-end=\"919\"><strong data-start=\"734\" data-end=\"748\">Enalapril:<\/strong> Inhibits angiotensin-converting enzyme (ACE), reducing angiotensin II levels, leading to <strong data-start=\"838\" data-end=\"854\">vasodilation<\/strong> and decreased aldosterone-mediated sodium and water retention.<\/p>\n<\/li>\n<li data-start=\"920\" data-end=\"1045\">\n<p data-start=\"922\" data-end=\"1045\"><strong data-start=\"922\" data-end=\"946\">Hydrochlorothiazide:<\/strong> Increases sodium and water excretion, reducing blood volume and further lowering blood pressure.<\/p>\n<\/li>\n<li data-start=\"1046\" data-end=\"1148\">\n<p data-start=\"1048\" data-end=\"1148\">The combination provides <strong data-start=\"1073\" data-end=\"1112\">synergistic antihypertensive effect<\/strong> through complementary mechanisms.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1150\" data-end=\"1168\"><strong data-start=\"1150\" data-end=\"1166\">Precautions:<\/strong><\/p>\n<ul data-start=\"1169\" data-end=\"1596\">\n<li data-start=\"1169\" data-end=\"1369\">\n<p data-start=\"1171\" data-end=\"1192\">Contraindicated in:<\/p>\n<ul data-start=\"1195\" data-end=\"1369\">\n<li data-start=\"1195\" data-end=\"1226\">\n<p data-start=\"1197\" data-end=\"1226\">Pregnancy and breastfeeding<\/p>\n<\/li>\n<li data-start=\"1229\" data-end=\"1280\">\n<p data-start=\"1231\" data-end=\"1280\">History of angioedema related to ACE inhibitors<\/p>\n<\/li>\n<li data-start=\"1283\" data-end=\"1310\">\n<p data-start=\"1285\" data-end=\"1310\">Severe renal impairment<\/p>\n<\/li>\n<li data-start=\"1313\" data-end=\"1369\">\n<p data-start=\"1315\" data-end=\"1369\">Hypersensitivity to enalapril or hydrochlorothiazide<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li data-start=\"1370\" data-end=\"1519\">\n<p data-start=\"1372\" data-end=\"1394\">Use with caution in:<\/p>\n<ul data-start=\"1397\" data-end=\"1519\">\n<li data-start=\"1397\" data-end=\"1446\">\n<p data-start=\"1399\" data-end=\"1446\">Electrolyte imbalances (especially potassium)<\/p>\n<\/li>\n<li data-start=\"1449\" data-end=\"1479\">\n<p data-start=\"1451\" data-end=\"1479\">Kidney or liver impairment<\/p>\n<\/li>\n<li data-start=\"1482\" data-end=\"1519\">\n<p data-start=\"1484\" data-end=\"1519\">Heart failure or volume depletion<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li data-start=\"1520\" data-end=\"1596\">\n<p data-start=\"1522\" data-end=\"1596\">Monitor <strong data-start=\"1530\" data-end=\"1583\">blood pressure, kidney function, and electrolytes<\/strong> regularly.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1598\" data-end=\"1626\"><strong data-start=\"1598\" data-end=\"1624\">Possible Side Effects:<\/strong><\/p>\n<ul data-start=\"1627\" data-end=\"1837\">\n<li data-start=\"1627\" data-end=\"1659\">\n<p data-start=\"1629\" data-end=\"1659\">Dizziness or lightheadedness<\/p>\n<\/li>\n<li data-start=\"1660\" data-end=\"1671\">\n<p data-start=\"1662\" data-end=\"1671\">Fatigue<\/p>\n<\/li>\n<li data-start=\"1672\" data-end=\"1705\">\n<p data-start=\"1674\" data-end=\"1705\">Cough (ACE inhibitor-related)<\/p>\n<\/li>\n<li data-start=\"1706\" data-end=\"1763\">\n<p data-start=\"1708\" data-end=\"1763\">Electrolyte disturbances (low sodium, high potassium)<\/p>\n<\/li>\n<li data-start=\"1764\" data-end=\"1784\">\n<p data-start=\"1766\" data-end=\"1784\">Peripheral edema<\/p>\n<\/li>\n<li data-start=\"1785\" data-end=\"1837\">\n<p data-start=\"1787\" data-end=\"1837\">Rare: angioedema, hypotension, kidney impairment<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1839\" data-end=\"1853\"><strong data-start=\"1839\" data-end=\"1851\">Storage:<\/strong><\/p>\n<ul data-start=\"1854\" data-end=\"1958\" data-is-last-node=\"\" data-is-only-node=\"\">\n<li data-start=\"1854\" data-end=\"1925\">\n<p data-start=\"1856\" data-end=\"1925\">Store below 25\u00b0C in a dry place, protected from light and moisture.<\/p>\n<\/li>\n<li data-start=\"1926\" data-end=\"1958\" data-is-last-node=\"\">\n<p data-start=\"1928\" data-end=\"1958\" data-is-last-node=\"\">Keep out of reach of children.<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"z-0 flex min-h-[46px] justify-start\"><\/div>\n<div class=\"mt-3 w-full empty:hidden\">\n<div class=\"text-center\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<div class=\"pointer-events-none h-px w-px\" aria-hidden=\"true\" data-edge=\"true\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Ezapril Co 20\/12.5 mg (30 Tablets) Active Ingredients: Enalapril 20 mg (ACE inhibitor) Hydrochlorothiazide 12.5 mg (Thiazide diuretic) Therapeutic Class:Combination antihypertensive \u2013 ACE inhibitor + Thiazide diuretic Indications: Hypertension (high blood pressure) in adults, especially when monotherapy is insufficient. May be used to reduce cardiovascular risk in patients requiring dual therapy. Dosage: Usual adult dose:&#8230;<\/p>\n","protected":false},"featured_media":4216,"comment_status":"open","ping_status":"closed","template":"","meta":{"rs_blank_template":"","rs_page_bg_color":"","slide_template_v7":"","_bst_post_transparent":"default","_bst_post_title":"","_bst_post_layout":"default","_bst_post_sidebar_id":"","_bst_post_content_style":"default","_bst_post_vertical_padding":"default","_bst_post_feature":"","_bst_post_feature_position":"","_bst_post_header":false,"_bst_post_footer":false},"product_brand":[],"product_cat":[80,45],"product_tag":[],"product_brands":[],"class_list":{"0":"post-4010","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-cardiovascular-blood-pressure","7":"product_cat-medicines","9":"first","10":"instock","11":"shipping-taxable","12":"purchasable","13":"product-type-simple","14":"entry","15":"content-bg","16":"loop-entry"},"_links":{"self":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product\/4010","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/comments?post=4010"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/media\/4216"}],"wp:attachment":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/media?parent=4010"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_brand?post=4010"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_cat?post=4010"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_tag?post=4010"},{"taxonomy":"product_brands","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_brands?post=4010"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}