{"id":4004,"date":"2025-10-24T08:17:22","date_gmt":"2025-10-24T08:17:22","guid":{"rendered":"https:\/\/nawarpharmacy.com\/?post_type=product&#038;p=4004"},"modified":"2025-10-25T13:34:03","modified_gmt":"2025-10-25T13:34:03","slug":"erastapex-co-4010mg-30-tablets","status":"publish","type":"product","link":"https:\/\/nawarpharmacy.com\/ru\/product\/erastapex-co-4010mg-30-tablets\/","title":{"rendered":"Erastapex Co 40\\10mg 30 Tablets"},"content":{"rendered":"<p data-start=\"0\" data-end=\"40\"><strong data-start=\"0\" data-end=\"38\">Erastapex Co 40\/10 mg (30 Tablets)<\/strong><\/p>\n<p data-start=\"42\" data-end=\"67\"><strong data-start=\"42\" data-end=\"65\">Active Ingredients:<\/strong><\/p>\n<ul data-start=\"68\" data-end=\"183\">\n<li data-start=\"68\" data-end=\"129\">\n<p data-start=\"70\" data-end=\"129\"><strong data-start=\"70\" data-end=\"88\">Losartan 40 mg<\/strong> (Angiotensin II receptor blocker, ARB)<\/p>\n<\/li>\n<li data-start=\"130\" data-end=\"183\">\n<p data-start=\"132\" data-end=\"183\"><strong data-start=\"132\" data-end=\"161\">Hydrochlorothiazide 10 mg<\/strong> (Thiazide diuretic)<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"185\" data-end=\"266\"><strong data-start=\"185\" data-end=\"207\">Therapeutic Class:<\/strong><br data-start=\"207\" data-end=\"210\" \/>Combination antihypertensive \u2013 ARB + Thiazide diuretic<\/p>\n<p data-start=\"268\" data-end=\"286\"><strong data-start=\"268\" data-end=\"284\">Indications:<\/strong><\/p>\n<ul data-start=\"287\" data-end=\"484\">\n<li data-start=\"287\" data-end=\"387\">\n<p data-start=\"289\" data-end=\"387\"><strong data-start=\"289\" data-end=\"327\">Hypertension (high blood pressure)<\/strong> in adults, particularly when monotherapy is insufficient.<\/p>\n<\/li>\n<li data-start=\"388\" data-end=\"484\">\n<p data-start=\"390\" data-end=\"484\">May help reduce <strong data-start=\"406\" data-end=\"429\">cardiovascular risk<\/strong> and protect <strong data-start=\"442\" data-end=\"460\">renal function<\/strong> in selected patients.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"486\" data-end=\"499\"><strong data-start=\"486\" data-end=\"497\">Dosage:<\/strong><\/p>\n<ul data-start=\"500\" data-end=\"734\">\n<li data-start=\"500\" data-end=\"575\">\n<p data-start=\"502\" data-end=\"575\"><strong data-start=\"502\" data-end=\"523\">Usual adult dose:<\/strong> One tablet once daily, preferably in the morning.<\/p>\n<\/li>\n<li data-start=\"576\" data-end=\"618\">\n<p data-start=\"578\" data-end=\"618\">Can be taken <strong data-start=\"591\" data-end=\"615\">with or without food<\/strong>.<\/p>\n<\/li>\n<li data-start=\"619\" data-end=\"734\">\n<p data-start=\"621\" data-end=\"734\">Dose adjustments may be required based on <strong data-start=\"663\" data-end=\"731\">blood pressure response, kidney function, and electrolyte levels<\/strong>.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"736\" data-end=\"762\"><strong data-start=\"736\" data-end=\"760\">Mechanism of Action:<\/strong><\/p>\n<ul data-start=\"763\" data-end=\"1110\">\n<li data-start=\"763\" data-end=\"881\">\n<p data-start=\"765\" data-end=\"881\"><strong data-start=\"765\" data-end=\"778\">Losartan:<\/strong> Blocks angiotensin II type 1 (AT1) receptors, preventing vasoconstriction and aldosterone secretion.<\/p>\n<\/li>\n<li data-start=\"882\" data-end=\"1007\">\n<p data-start=\"884\" data-end=\"1007\"><strong data-start=\"884\" data-end=\"908\">Hydrochlorothiazide:<\/strong> Increases sodium and water excretion, reducing blood volume and further lowering blood pressure.<\/p>\n<\/li>\n<li data-start=\"1008\" data-end=\"1110\">\n<p data-start=\"1010\" data-end=\"1110\">The combination provides <strong data-start=\"1035\" data-end=\"1074\">synergistic antihypertensive effect<\/strong> through complementary mechanisms.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1112\" data-end=\"1130\"><strong data-start=\"1112\" data-end=\"1128\">Precautions:<\/strong><\/p>\n<ul data-start=\"1131\" data-end=\"1503\">\n<li data-start=\"1131\" data-end=\"1276\">\n<p data-start=\"1133\" data-end=\"1154\">Contraindicated in:<\/p>\n<ul data-start=\"1157\" data-end=\"1276\">\n<li data-start=\"1157\" data-end=\"1188\">\n<p data-start=\"1159\" data-end=\"1188\">Pregnancy and breastfeeding<\/p>\n<\/li>\n<li data-start=\"1191\" data-end=\"1218\">\n<p data-start=\"1193\" data-end=\"1218\">Severe renal impairment<\/p>\n<\/li>\n<li data-start=\"1221\" data-end=\"1276\">\n<p data-start=\"1223\" data-end=\"1276\">Hypersensitivity to losartan or hydrochlorothiazide<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li data-start=\"1277\" data-end=\"1426\">\n<p data-start=\"1279\" data-end=\"1301\">Use with caution in:<\/p>\n<ul data-start=\"1304\" data-end=\"1426\">\n<li data-start=\"1304\" data-end=\"1353\">\n<p data-start=\"1306\" data-end=\"1353\">Electrolyte imbalances (especially potassium)<\/p>\n<\/li>\n<li data-start=\"1356\" data-end=\"1386\">\n<p data-start=\"1358\" data-end=\"1386\">Kidney or liver impairment<\/p>\n<\/li>\n<li data-start=\"1389\" data-end=\"1426\">\n<p data-start=\"1391\" data-end=\"1426\">Heart failure or volume depletion<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li data-start=\"1427\" data-end=\"1503\">\n<p data-start=\"1429\" data-end=\"1503\">Monitor <strong data-start=\"1437\" data-end=\"1490\">blood pressure, kidney function, and electrolytes<\/strong> regularly.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1505\" data-end=\"1533\"><strong data-start=\"1505\" data-end=\"1531\">Possible Side Effects:<\/strong><\/p>\n<ul data-start=\"1534\" data-end=\"1721\">\n<li data-start=\"1534\" data-end=\"1566\">\n<p data-start=\"1536\" data-end=\"1566\">Dizziness or lightheadedness<\/p>\n<\/li>\n<li data-start=\"1567\" data-end=\"1578\">\n<p data-start=\"1569\" data-end=\"1578\">Fatigue<\/p>\n<\/li>\n<li data-start=\"1579\" data-end=\"1636\">\n<p data-start=\"1581\" data-end=\"1636\">Electrolyte disturbances (low sodium, high potassium)<\/p>\n<\/li>\n<li data-start=\"1637\" data-end=\"1652\">\n<p data-start=\"1639\" data-end=\"1652\">Hypotension<\/p>\n<\/li>\n<li data-start=\"1653\" data-end=\"1673\">\n<p data-start=\"1655\" data-end=\"1673\">Peripheral edema<\/p>\n<\/li>\n<li data-start=\"1674\" data-end=\"1721\">\n<p data-start=\"1676\" data-end=\"1721\">Rare: kidney impairment, allergic reactions<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1723\" data-end=\"1737\"><strong data-start=\"1723\" data-end=\"1735\">Storage:<\/strong><\/p>\n<ul data-start=\"1738\" data-end=\"1840\" data-is-last-node=\"\" data-is-only-node=\"\">\n<li data-start=\"1738\" data-end=\"1808\">\n<p data-start=\"1740\" data-end=\"1808\">Store below 25\u00b0C in a dry place, protected from light and moisture<\/p>\n<\/li>\n<li data-start=\"1809\" data-end=\"1840\" data-is-last-node=\"\">\n<p data-start=\"1811\" data-end=\"1840\" data-is-last-node=\"\">Keep out of reach of children<\/p>\n<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Erastapex Co 40\/10 mg (30 Tablets) Active Ingredients: Losartan 40 mg (Angiotensin II receptor blocker, ARB) Hydrochlorothiazide 10 mg (Thiazide diuretic) Therapeutic Class:Combination antihypertensive \u2013 ARB + Thiazide diuretic Indications: Hypertension (high blood pressure) in adults, particularly when monotherapy is insufficient. May help reduce cardiovascular risk and protect renal function in selected patients. Dosage: Usual&#8230;<\/p>\n","protected":false},"featured_media":4228,"comment_status":"open","ping_status":"closed","template":"","meta":{"rs_blank_template":"","rs_page_bg_color":"","slide_template_v7":"","_bst_post_transparent":"default","_bst_post_title":"","_bst_post_layout":"default","_bst_post_sidebar_id":"","_bst_post_content_style":"default","_bst_post_vertical_padding":"default","_bst_post_feature":"","_bst_post_feature_position":"","_bst_post_header":false,"_bst_post_footer":false},"product_brand":[],"product_cat":[80,45],"product_tag":[],"product_brands":[],"class_list":{"0":"post-4004","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-cardiovascular-blood-pressure","7":"product_cat-medicines","9":"first","10":"instock","11":"shipping-taxable","12":"purchasable","13":"product-type-simple","14":"entry","15":"content-bg","16":"loop-entry"},"_links":{"self":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product\/4004","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/comments?post=4004"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/media\/4228"}],"wp:attachment":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/media?parent=4004"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_brand?post=4004"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_cat?post=4004"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_tag?post=4004"},{"taxonomy":"product_brands","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_brands?post=4004"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}