{"id":3999,"date":"2025-10-24T08:13:29","date_gmt":"2025-10-24T08:13:29","guid":{"rendered":"https:\/\/nawarpharmacy.com\/?post_type=product&p=3999"},"modified":"2025-10-25T13:47:51","modified_gmt":"2025-10-25T13:47:51","slug":"erastapex-plus-4012-5mg-30-tablets","status":"publish","type":"product","link":"https:\/\/nawarpharmacy.com\/ru\/product\/erastapex-plus-4012-5mg-30-tablets\/","title":{"rendered":"Erastapex Plus 40\\12.5mg 30 Tablets"},"content":{"rendered":"
\n
\n
\n
\n
\n
\n
\n

Erastapex Plus 40\/12.5 mg (30 Tablets)<\/strong><\/p>\n

Active Ingredients:<\/strong><\/p>\n

    \n
  • \n

    Losartan 40 mg<\/strong> (Angiotensin II receptor blocker, ARB)<\/p>\n<\/li>\n

  • \n

    Hydrochlorothiazide 12.5 mg<\/strong> (Thiazide diuretic)<\/p>\n<\/li>\n<\/ul>\n

    Therapeutic Class:<\/strong>
    Combination antihypertensive \u2013 ARB + Thiazide diuretic<\/p>\n

    Indications:<\/strong><\/p>\n

      \n
    • \n

      Hypertension (high blood pressure)<\/strong> in adults, especially when monotherapy is insufficient.<\/p>\n<\/li>\n

    • \n

      May help reduce cardiovascular risk<\/strong> and protect renal function<\/strong> in selected patients.<\/p>\n<\/li>\n<\/ul>\n

      Dosage:<\/strong><\/p>\n

        \n
      • \n

        Usual adult dose:<\/strong> One tablet once daily, preferably in the morning.<\/p>\n<\/li>\n

      • \n

        Can be taken with or without food<\/strong>.<\/p>\n<\/li>\n

      • \n

        Dose adjustments may be required based on blood pressure response, kidney function, and electrolyte levels<\/strong>.<\/p>\n<\/li>\n<\/ul>\n

        Mechanism of Action:<\/strong><\/p>\n

          \n
        • \n

          Losartan:<\/strong> Blocks angiotensin II type 1 (AT1) receptors, preventing vasoconstriction and aldosterone secretion.<\/p>\n<\/li>\n

        • \n

          Hydrochlorothiazide:<\/strong> Increases sodium and water excretion, reducing blood volume and lowering blood pressure.<\/p>\n<\/li>\n

        • \n

          The combination provides synergistic antihypertensive effect<\/strong> through complementary mechanisms.<\/p>\n<\/li>\n<\/ul>\n

          Precautions:<\/strong><\/p>\n

            \n
          • \n

            Contraindicated in:<\/p>\n

              \n
            • \n

              Pregnancy and breastfeeding<\/p>\n<\/li>\n

            • \n

              Severe renal impairment<\/p>\n<\/li>\n

            • \n

              Hypersensitivity to losartan or hydrochlorothiazide<\/p>\n<\/li>\n<\/ul>\n<\/li>\n

            • \n

              Use with caution in:<\/p>\n

                \n
              • \n

                Electrolyte imbalances (especially potassium)<\/p>\n<\/li>\n

              • \n

                Kidney or liver impairment<\/p>\n<\/li>\n

              • \n

                Heart failure or volume depletion<\/p>\n<\/li>\n<\/ul>\n<\/li>\n

              • \n

                Monitor blood pressure, kidney function, and electrolytes<\/strong> regularly.<\/p>\n<\/li>\n<\/ul>\n

                Possible Side Effects:<\/strong><\/p>\n

                  \n
                • \n

                  Dizziness or lightheadedness<\/p>\n<\/li>\n

                • \n

                  Fatigue<\/p>\n<\/li>\n

                • \n

                  Electrolyte disturbances (low sodium, high potassium)<\/p>\n<\/li>\n

                • \n

                  Hypotension<\/p>\n<\/li>\n

                • \n

                  Peripheral edema<\/p>\n<\/li>\n

                • \n

                  Rare: kidney impairment, angioedema, allergic reactions<\/p>\n<\/li>\n<\/ul>\n

                  Storage:<\/strong><\/p>\n

                    \n
                  • \n

                    Store below 25\u00b0C in a dry place, protected from light and moisture<\/p>\n<\/li>\n

                  • \n

                    Keep out of reach of children<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

                    <\/div>\n
                    \n
                    <\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n
                    <\/div>\n","protected":false},"excerpt":{"rendered":"

                    Erastapex Plus 40\/12.5 mg (30 Tablets) Active Ingredients: Losartan 40 mg (Angiotensin II receptor blocker, ARB) Hydrochlorothiazide 12.5 mg (Thiazide diuretic) Therapeutic Class:Combination antihypertensive \u2013 ARB + Thiazide diuretic Indications: Hypertension (high blood pressure) in adults, especially when monotherapy is insufficient. May help reduce cardiovascular risk and protect renal function in selected patients. Dosage: Usual…<\/p>\n","protected":false},"featured_media":4238,"comment_status":"open","ping_status":"closed","template":"","meta":{"rs_blank_template":"","rs_page_bg_color":"","slide_template_v7":"","_bst_post_transparent":"default","_bst_post_title":"","_bst_post_layout":"default","_bst_post_sidebar_id":"","_bst_post_content_style":"default","_bst_post_vertical_padding":"default","_bst_post_feature":"","_bst_post_feature_position":"","_bst_post_header":false,"_bst_post_footer":false},"product_brand":[],"product_cat":[80,45],"product_tag":[],"product_brands":[],"class_list":{"0":"post-3999","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-cardiovascular-blood-pressure","7":"product_cat-medicines","9":"first","10":"instock","11":"shipping-taxable","12":"purchasable","13":"product-type-simple","14":"entry","15":"content-bg","16":"loop-entry"},"_links":{"self":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product\/3999","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/comments?post=3999"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/media\/4238"}],"wp:attachment":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/media?parent=3999"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_brand?post=3999"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_cat?post=3999"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_tag?post=3999"},{"taxonomy":"product_brands","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_brands?post=3999"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}