{"id":3973,"date":"2025-10-24T07:51:17","date_gmt":"2025-10-24T07:51:17","guid":{"rendered":"https:\/\/nawarpharmacy.com\/?post_type=product&#038;p=3973"},"modified":"2025-11-04T12:38:57","modified_gmt":"2025-11-04T12:38:57","slug":"epi-dinitra-10mg-20-tablets","status":"publish","type":"product","link":"https:\/\/nawarpharmacy.com\/ru\/product\/epi-dinitra-10mg-20-tablets\/","title":{"rendered":"Epi-Dinitra 10mg 20 Tablets"},"content":{"rendered":"<article class=\"text-token-text-primary w-full focus:outline-none [--shadow-height:45px] has-data-writing-block:pointer-events-none has-data-writing-block:-mt-(--shadow-height) has-data-writing-block:pt-(--shadow-height) [&amp;:has([data-writing-block])&gt;*]:pointer-events-auto [content-visibility:auto] supports-[content-visibility:auto]:[contain-intrinsic-size:auto_100lvh] scroll-mt-[calc(var(--header-height)+min(200px,max(70px,20svh)))]\" dir=\"auto\" data-turn-id=\"request-68f645cb-9280-8327-a300-008dc440122c-2\" data-testid=\"conversation-turn-239\" data-scroll-anchor=\"true\" data-turn=\"assistant\">\n<div class=\"text-base my-auto mx-auto pb-10 [--thread-content-margin:--spacing(4)] thread-sm:[--thread-content-margin:--spacing(6)] thread-lg:[--thread-content-margin:--spacing(16)] px-(--thread-content-margin)\">\n<div class=\"[--thread-content-max-width:40rem] thread-lg:[--thread-content-max-width:48rem] mx-auto max-w-(--thread-content-max-width) flex-1 group\/turn-messages focus-visible:outline-hidden relative flex w-full min-w-0 flex-col agent-turn\">\n<div class=\"flex max-w-full flex-col grow\">\n<div class=\"min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal [.text-message+&amp;]:mt-1\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"b128b865-e977-41e8-854b-d7239967aab3\" data-message-model-slug=\"gpt-5\">\n<div class=\"flex w-full flex-col gap-1 empty:hidden first:pt-[1px]\">\n<div class=\"markdown prose dark:prose-invert w-full break-words light markdown-new-styling\">\n<p data-start=\"0\" data-end=\"36\"><strong data-start=\"0\" data-end=\"34\">Epi-Dinitra 10 mg (20 Tablets)<\/strong><\/p>\n<p data-start=\"38\" data-end=\"62\"><strong data-start=\"38\" data-end=\"60\">Active Ingredient:<\/strong><\/p>\n<ul data-start=\"63\" data-end=\"119\">\n<li data-start=\"63\" data-end=\"119\">\n<p data-start=\"65\" data-end=\"119\"><strong data-start=\"65\" data-end=\"95\">Isosorbide Dinitrate 10 mg<\/strong> \u2013 Nitrate vasodilator<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"121\" data-end=\"175\"><strong data-start=\"121\" data-end=\"143\">Therapeutic Class:<\/strong><br data-start=\"143\" data-end=\"146\" \/>Antianginal and vasodilator<\/p>\n<p data-start=\"177\" data-end=\"195\"><strong data-start=\"177\" data-end=\"193\">Indications:<\/strong><\/p>\n<ul data-start=\"196\" data-end=\"466\">\n<li data-start=\"196\" data-end=\"291\">\n<p data-start=\"198\" data-end=\"291\"><strong data-start=\"198\" data-end=\"245\">Prevention and treatment of angina pectoris<\/strong> (chest pain due to coronary artery disease)<\/p>\n<\/li>\n<li data-start=\"292\" data-end=\"382\">\n<p data-start=\"294\" data-end=\"382\"><strong data-start=\"294\" data-end=\"325\">Management of heart failure<\/strong>, usually in combination with other cardiac medications<\/p>\n<\/li>\n<li data-start=\"383\" data-end=\"466\">\n<p data-start=\"385\" data-end=\"466\"><strong data-start=\"385\" data-end=\"420\">Relief of ischemic cardiac pain<\/strong> by improving blood flow to the heart muscle<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"468\" data-end=\"481\"><strong data-start=\"468\" data-end=\"479\">Dosage:<\/strong><\/p>\n<ul data-start=\"482\" data-end=\"733\">\n<li data-start=\"482\" data-end=\"562\">\n<p data-start=\"484\" data-end=\"562\"><strong data-start=\"484\" data-end=\"507\">Typical adult dose:<\/strong> 10\u201340 mg taken <strong data-start=\"523\" data-end=\"545\">2 to 3 times daily<\/strong>, as prescribed<\/p>\n<\/li>\n<li data-start=\"563\" data-end=\"636\">\n<p data-start=\"565\" data-end=\"636\">Should be taken <strong data-start=\"581\" data-end=\"595\">with water<\/strong>, preferably at the same times each day<\/p>\n<\/li>\n<li data-start=\"637\" data-end=\"733\">\n<p data-start=\"639\" data-end=\"733\">A <strong data-start=\"641\" data-end=\"686\">nitrate-free interval (at least 12 hours)<\/strong> each day is recommended to prevent tolerance<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"735\" data-end=\"761\"><strong data-start=\"735\" data-end=\"759\">Mechanism of Action:<\/strong><\/p>\n<ul data-start=\"762\" data-end=\"1032\">\n<li data-start=\"762\" data-end=\"853\">\n<p data-start=\"764\" data-end=\"853\">Isosorbide dinitrate is converted to nitric oxide, which relaxes vascular smooth muscle<\/p>\n<\/li>\n<li data-start=\"854\" data-end=\"937\">\n<p data-start=\"856\" data-end=\"937\">Causes <strong data-start=\"863\" data-end=\"895\">venous and arterial dilation<\/strong>, reducing cardiac preload and afterload<\/p>\n<\/li>\n<li data-start=\"938\" data-end=\"1032\">\n<p data-start=\"940\" data-end=\"1032\">Improves oxygen delivery to the myocardium, relieving angina and reducing cardiac workload<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1034\" data-end=\"1052\"><strong data-start=\"1034\" data-end=\"1050\">Precautions:<\/strong><\/p>\n<ul data-start=\"1053\" data-end=\"1537\">\n<li data-start=\"1053\" data-end=\"1311\">\n<p data-start=\"1055\" data-end=\"1076\">Contraindicated in:<\/p>\n<ul data-start=\"1079\" data-end=\"1311\">\n<li data-start=\"1079\" data-end=\"1114\">\n<p data-start=\"1081\" data-end=\"1114\"><strong data-start=\"1081\" data-end=\"1112\">Severe hypotension or shock<\/strong><\/p>\n<\/li>\n<li data-start=\"1117\" data-end=\"1248\">\n<p data-start=\"1119\" data-end=\"1248\"><strong data-start=\"1119\" data-end=\"1170\">Concomitant use of phosphodiesterase inhibitors<\/strong> (e.g., sildenafil, tadalafil, vardenafil) due to risk of severe hypotension<\/p>\n<\/li>\n<li data-start=\"1251\" data-end=\"1311\">\n<p data-start=\"1253\" data-end=\"1311\"><strong data-start=\"1253\" data-end=\"1270\">Severe anemia<\/strong> or <strong data-start=\"1274\" data-end=\"1309\">increased intracranial pressure<\/strong><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li data-start=\"1312\" data-end=\"1478\">\n<p data-start=\"1314\" data-end=\"1336\">Use with caution in:<\/p>\n<ul data-start=\"1339\" data-end=\"1478\">\n<li data-start=\"1339\" data-end=\"1423\">\n<p data-start=\"1341\" data-end=\"1423\">Patients with <strong data-start=\"1355\" data-end=\"1370\">hypotension<\/strong>, <strong data-start=\"1372\" data-end=\"1392\">volume depletion<\/strong>, or <strong data-start=\"1397\" data-end=\"1421\">orthostatic symptoms<\/strong><\/p>\n<\/li>\n<li data-start=\"1426\" data-end=\"1478\">\n<p data-start=\"1428\" data-end=\"1478\">Those with <strong data-start=\"1439\" data-end=\"1451\">glaucoma<\/strong> or <strong data-start=\"1455\" data-end=\"1476\">thyroid disorders<\/strong><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li data-start=\"1479\" data-end=\"1537\">\n<p data-start=\"1481\" data-end=\"1537\">Avoid abrupt discontinuation to prevent rebound angina<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1539\" data-end=\"1567\"><strong data-start=\"1539\" data-end=\"1565\">Possible Side Effects:<\/strong><\/p>\n<ul data-start=\"1568\" data-end=\"1835\">\n<li data-start=\"1568\" data-end=\"1635\">\n<p data-start=\"1570\" data-end=\"1635\"><strong data-start=\"1570\" data-end=\"1582\">Headache<\/strong> (very common, usually improves with continued use)<\/p>\n<\/li>\n<li data-start=\"1636\" data-end=\"1702\">\n<p data-start=\"1638\" data-end=\"1702\"><strong data-start=\"1638\" data-end=\"1670\">Dizziness or lightheadedness<\/strong> (especially when standing up)<\/p>\n<\/li>\n<li data-start=\"1703\" data-end=\"1729\">\n<p data-start=\"1705\" data-end=\"1729\"><strong data-start=\"1705\" data-end=\"1727\">Flushing or warmth<\/strong><\/p>\n<\/li>\n<li data-start=\"1730\" data-end=\"1770\">\n<p data-start=\"1732\" data-end=\"1770\"><strong data-start=\"1732\" data-end=\"1768\">Low blood pressure (hypotension)<\/strong><\/p>\n<\/li>\n<li data-start=\"1771\" data-end=\"1835\">\n<p data-start=\"1773\" data-end=\"1835\">Rare: Reflex tachycardia, nausea, or allergic skin reactions<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1837\" data-end=\"1851\"><strong data-start=\"1837\" data-end=\"1849\">Storage:<\/strong><\/p>\n<ul data-start=\"1852\" data-end=\"1954\" data-is-last-node=\"\" data-is-only-node=\"\">\n<li data-start=\"1852\" data-end=\"1922\">\n<p data-start=\"1854\" data-end=\"1922\">Store below 25\u00b0C in a dry place, protected from light and moisture<\/p>\n<\/li>\n<li data-start=\"1923\" data-end=\"1954\" data-is-last-node=\"\">\n<p data-start=\"1925\" data-end=\"1954\" data-is-last-node=\"\">Keep out of reach of children<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"z-0 flex min-h-[46px] justify-start\"><\/div>\n<div class=\"mt-3 w-full empty:hidden\">\n<div class=\"text-center\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<div class=\"pointer-events-none h-px w-px\" aria-hidden=\"true\" data-edge=\"true\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Epi-Dinitra 10 mg (20 Tablets) Active Ingredient: Isosorbide Dinitrate 10 mg \u2013 Nitrate vasodilator Therapeutic Class:Antianginal and vasodilator Indications: Prevention and treatment of angina pectoris (chest pain due to coronary artery disease) Management of heart failure, usually in combination with other cardiac medications Relief of ischemic cardiac pain by improving blood flow to the heart&#8230;<\/p>\n","protected":false},"featured_media":4672,"comment_status":"open","ping_status":"closed","template":"","meta":{"rs_blank_template":"","rs_page_bg_color":"","slide_template_v7":"","_bst_post_transparent":"default","_bst_post_title":"","_bst_post_layout":"default","_bst_post_sidebar_id":"","_bst_post_content_style":"default","_bst_post_vertical_padding":"default","_bst_post_feature":"","_bst_post_feature_position":"","_bst_post_header":false,"_bst_post_footer":false},"product_brand":[],"product_cat":[80,45],"product_tag":[],"product_brands":[],"class_list":{"0":"post-3973","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-cardiovascular-blood-pressure","7":"product_cat-medicines","9":"first","10":"instock","11":"shipping-taxable","12":"purchasable","13":"product-type-simple","14":"entry","15":"content-bg","16":"loop-entry"},"_links":{"self":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product\/3973","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/comments?post=3973"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/media\/4672"}],"wp:attachment":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/media?parent=3973"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_brand?post=3973"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_cat?post=3973"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_tag?post=3973"},{"taxonomy":"product_brands","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_brands?post=3973"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}