{"id":3972,"date":"2025-10-24T07:50:22","date_gmt":"2025-10-24T07:50:22","guid":{"rendered":"https:\/\/nawarpharmacy.com\/?post_type=product&#038;p=3972"},"modified":"2025-11-04T12:39:38","modified_gmt":"2025-11-04T12:39:38","slug":"epi-dinitra-5mg-30-sublingual-tablets","status":"publish","type":"product","link":"https:\/\/nawarpharmacy.com\/ru\/product\/epi-dinitra-5mg-30-sublingual-tablets\/","title":{"rendered":"Epi-Dinitra 5mg 30 Sublingual Tablets"},"content":{"rendered":"<article class=\"text-token-text-primary w-full focus:outline-none [--shadow-height:45px] has-data-writing-block:pointer-events-none has-data-writing-block:-mt-(--shadow-height) has-data-writing-block:pt-(--shadow-height) [&amp;:has([data-writing-block])&gt;*]:pointer-events-auto [content-visibility:auto] supports-[content-visibility:auto]:[contain-intrinsic-size:auto_100lvh] scroll-mt-[calc(var(--header-height)+min(200px,max(70px,20svh)))]\" dir=\"auto\" data-turn-id=\"request-68f645cb-9280-8327-a300-008dc440122c-5\" data-testid=\"conversation-turn-245\" data-scroll-anchor=\"true\" data-turn=\"assistant\">\n<div class=\"text-base my-auto mx-auto pb-10 [--thread-content-margin:--spacing(4)] thread-sm:[--thread-content-margin:--spacing(6)] thread-lg:[--thread-content-margin:--spacing(16)] px-(--thread-content-margin)\">\n<div class=\"[--thread-content-max-width:40rem] thread-lg:[--thread-content-max-width:48rem] mx-auto max-w-(--thread-content-max-width) flex-1 group\/turn-messages focus-visible:outline-hidden relative flex w-full min-w-0 flex-col agent-turn\">\n<div class=\"flex max-w-full flex-col grow\">\n<div class=\"min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal [.text-message+&amp;]:mt-1\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"842cfa1e-d919-4004-88ff-f3c98acdbf8a\" data-message-model-slug=\"gpt-5\">\n<div class=\"flex w-full flex-col gap-1 empty:hidden first:pt-[1px]\">\n<div class=\"markdown prose dark:prose-invert w-full break-words light markdown-new-styling\">\n<p data-start=\"0\" data-end=\"46\"><strong data-start=\"0\" data-end=\"44\">Epi-Dinitra 5 mg (30 Sublingual Tablets)<\/strong><\/p>\n<p data-start=\"48\" data-end=\"72\"><strong data-start=\"48\" data-end=\"70\">Active Ingredient:<\/strong><\/p>\n<ul data-start=\"73\" data-end=\"136\">\n<li data-start=\"73\" data-end=\"136\">\n<p data-start=\"75\" data-end=\"136\"><strong data-start=\"75\" data-end=\"104\">Isosorbide Dinitrate 5 mg<\/strong> \u2013 Organic nitrate vasodilator<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"138\" data-end=\"203\"><strong data-start=\"138\" data-end=\"160\">Therapeutic Class:<\/strong><br data-start=\"160\" data-end=\"163\" \/>Antianginal and vasodilator medication<\/p>\n<p data-start=\"205\" data-end=\"223\"><strong data-start=\"205\" data-end=\"221\">Indications:<\/strong><\/p>\n<ul data-start=\"224\" data-end=\"388\">\n<li data-start=\"224\" data-end=\"316\">\n<p data-start=\"226\" data-end=\"316\"><strong data-start=\"226\" data-end=\"270\">Relief and prevention of angina pectoris<\/strong> (chest pain due to coronary artery disease)<\/p>\n<\/li>\n<li data-start=\"317\" data-end=\"388\">\n<p data-start=\"319\" data-end=\"388\"><strong data-start=\"319\" data-end=\"357\">Adjunct treatment in heart failure<\/strong> (to reduce cardiac workload)<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"390\" data-end=\"422\"><strong data-start=\"390\" data-end=\"420\">Dosage and Administration:<\/strong><\/p>\n<ul data-start=\"423\" data-end=\"901\">\n<li data-start=\"423\" data-end=\"526\">\n<p data-start=\"425\" data-end=\"526\"><strong data-start=\"425\" data-end=\"449\">Acute angina attack:<\/strong> Place <strong data-start=\"456\" data-end=\"487\">one tablet under the tongue<\/strong> and allow it to dissolve completely.<\/p>\n<\/li>\n<li data-start=\"527\" data-end=\"596\">\n<p data-start=\"529\" data-end=\"596\">If pain persists after 5\u201310 minutes, another tablet may be taken.<\/p>\n<\/li>\n<li data-start=\"597\" data-end=\"683\">\n<p data-start=\"599\" data-end=\"683\"><strong data-start=\"599\" data-end=\"611\">Maximum:<\/strong> 3 tablets within 15\u201330 minutes (seek medical attention if no relief).<\/p>\n<\/li>\n<li data-start=\"684\" data-end=\"798\">\n<p data-start=\"686\" data-end=\"798\"><strong data-start=\"686\" data-end=\"702\">Prophylaxis:<\/strong> One tablet 15\u201330 minutes before activities likely to provoke angina (e.g., exertion, stress).<\/p>\n<\/li>\n<li data-start=\"799\" data-end=\"901\">\n<p data-start=\"801\" data-end=\"901\"><strong data-start=\"801\" data-end=\"819\">Do not swallow<\/strong> the tablet; sublingual absorption provides rapid onset of action (1\u20133 minutes).<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"903\" data-end=\"929\"><strong data-start=\"903\" data-end=\"927\">Mechanism of Action:<\/strong><\/p>\n<ul data-start=\"930\" data-end=\"1152\">\n<li data-start=\"930\" data-end=\"1015\">\n<p data-start=\"932\" data-end=\"1015\">Converts to <strong data-start=\"944\" data-end=\"960\">nitric oxide<\/strong> in vascular smooth muscle, causing <strong data-start=\"996\" data-end=\"1012\">vasodilation<\/strong>.<\/p>\n<\/li>\n<li data-start=\"1016\" data-end=\"1089\">\n<p data-start=\"1018\" data-end=\"1089\">Reduces <strong data-start=\"1026\" data-end=\"1051\">preload and afterload<\/strong>, lowering myocardial oxygen demand.<\/p>\n<\/li>\n<li data-start=\"1090\" data-end=\"1152\">\n<p data-start=\"1092\" data-end=\"1152\">Improves <strong data-start=\"1101\" data-end=\"1124\">coronary blood flow<\/strong> to ischemic heart tissue.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1154\" data-end=\"1172\"><strong data-start=\"1154\" data-end=\"1170\">Precautions:<\/strong><\/p>\n<ul data-start=\"1173\" data-end=\"1676\">\n<li data-start=\"1173\" data-end=\"1419\">\n<p data-start=\"1175\" data-end=\"1196\">Contraindicated in:<\/p>\n<ul data-start=\"1199\" data-end=\"1419\">\n<li data-start=\"1199\" data-end=\"1238\">\n<p data-start=\"1201\" data-end=\"1238\"><strong data-start=\"1201\" data-end=\"1223\">Severe hypotension<\/strong> or <strong data-start=\"1227\" data-end=\"1236\">shock<\/strong><\/p>\n<\/li>\n<li data-start=\"1241\" data-end=\"1356\">\n<p data-start=\"1243\" data-end=\"1356\"><strong data-start=\"1243\" data-end=\"1284\">Use of phosphodiesterase-5 inhibitors<\/strong> (e.g., sildenafil, tadalafil, vardenafil) within the last 24\u201348 hours<\/p>\n<\/li>\n<li data-start=\"1359\" data-end=\"1419\">\n<p data-start=\"1361\" data-end=\"1419\"><strong data-start=\"1361\" data-end=\"1378\">Severe anemia<\/strong> or <strong data-start=\"1382\" data-end=\"1417\">increased intracranial pressure<\/strong><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li data-start=\"1420\" data-end=\"1583\">\n<p data-start=\"1422\" data-end=\"1444\">Use with caution in:<\/p>\n<ul data-start=\"1447\" data-end=\"1583\">\n<li data-start=\"1447\" data-end=\"1511\">\n<p data-start=\"1449\" data-end=\"1511\"><strong data-start=\"1449\" data-end=\"1461\">Glaucoma<\/strong>, <strong data-start=\"1463\" data-end=\"1482\">thyroid disease<\/strong>, or <strong data-start=\"1487\" data-end=\"1509\">hepatic impairment<\/strong><\/p>\n<\/li>\n<li data-start=\"1514\" data-end=\"1583\">\n<p data-start=\"1516\" data-end=\"1583\">Patients with <strong data-start=\"1530\" data-end=\"1550\">volume depletion<\/strong> or <strong data-start=\"1554\" data-end=\"1581\">orthostatic hypotension<\/strong><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li data-start=\"1584\" data-end=\"1676\">\n<p data-start=\"1586\" data-end=\"1676\">Tolerance may develop with continuous use\u2014intermittent dosing schedules are recommended.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1678\" data-end=\"1706\"><strong data-start=\"1678\" data-end=\"1704\">Possible Side Effects:<\/strong><\/p>\n<ul data-start=\"1707\" data-end=\"1896\">\n<li data-start=\"1707\" data-end=\"1758\">\n<p data-start=\"1709\" data-end=\"1758\"><strong data-start=\"1709\" data-end=\"1721\">Headache<\/strong> (very common, due to vasodilation)<\/p>\n<\/li>\n<li data-start=\"1759\" data-end=\"1788\">\n<p data-start=\"1761\" data-end=\"1788\"><strong data-start=\"1761\" data-end=\"1786\">Flushing or dizziness<\/strong><\/p>\n<\/li>\n<li data-start=\"1789\" data-end=\"1835\">\n<p data-start=\"1791\" data-end=\"1835\"><strong data-start=\"1791\" data-end=\"1806\">Hypotension<\/strong> (especially when standing)<\/p>\n<\/li>\n<li data-start=\"1836\" data-end=\"1862\">\n<p data-start=\"1838\" data-end=\"1862\"><strong data-start=\"1838\" data-end=\"1860\">Reflex tachycardia<\/strong><\/p>\n<\/li>\n<li data-start=\"1863\" data-end=\"1896\">\n<p data-start=\"1865\" data-end=\"1896\"><strong data-start=\"1865\" data-end=\"1894\">Nausea or lightheadedness<\/strong><\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1898\" data-end=\"1912\"><strong data-start=\"1898\" data-end=\"1910\">Storage:<\/strong><\/p>\n<ul data-start=\"1913\" data-end=\"2032\" data-is-last-node=\"\" data-is-only-node=\"\">\n<li data-start=\"1913\" data-end=\"1999\">\n<p data-start=\"1915\" data-end=\"1999\">Store below 25\u00b0C in a tightly closed container, protected from light and moisture.<\/p>\n<\/li>\n<li data-start=\"2000\" data-end=\"2032\" data-is-last-node=\"\">\n<p data-start=\"2002\" data-end=\"2032\" data-is-last-node=\"\">Keep out of reach of children.<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"z-0 flex min-h-[46px] justify-start\"><\/div>\n<div class=\"mt-3 w-full empty:hidden\">\n<div class=\"text-center\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<div class=\"pointer-events-none h-px w-px\" aria-hidden=\"true\" data-edge=\"true\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Epi-Dinitra 5 mg (30 Sublingual Tablets) Active Ingredient: Isosorbide Dinitrate 5 mg \u2013 Organic nitrate vasodilator Therapeutic Class:Antianginal and vasodilator medication Indications: Relief and prevention of angina pectoris (chest pain due to coronary artery disease) Adjunct treatment in heart failure (to reduce cardiac workload) Dosage and Administration: Acute angina attack: Place one tablet under the&#8230;<\/p>\n","protected":false},"featured_media":4673,"comment_status":"open","ping_status":"closed","template":"","meta":{"rs_blank_template":"","rs_page_bg_color":"","slide_template_v7":"","_bst_post_transparent":"default","_bst_post_title":"","_bst_post_layout":"default","_bst_post_sidebar_id":"","_bst_post_content_style":"default","_bst_post_vertical_padding":"default","_bst_post_feature":"","_bst_post_feature_position":"","_bst_post_header":false,"_bst_post_footer":false},"product_brand":[],"product_cat":[80,45],"product_tag":[],"product_brands":[],"class_list":{"0":"post-3972","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-cardiovascular-blood-pressure","7":"product_cat-medicines","9":"first","10":"instock","11":"shipping-taxable","12":"purchasable","13":"product-type-simple","14":"entry","15":"content-bg","16":"loop-entry"},"_links":{"self":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product\/3972","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/comments?post=3972"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/media\/4673"}],"wp:attachment":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/media?parent=3972"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_brand?post=3972"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_cat?post=3972"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_tag?post=3972"},{"taxonomy":"product_brands","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_brands?post=3972"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}