{"id":3611,"date":"2025-10-20T12:36:18","date_gmt":"2025-10-20T12:36:18","guid":{"rendered":"https:\/\/nawarpharmacy.com\/?post_type=product&#038;p=3611"},"modified":"2025-10-21T12:37:12","modified_gmt":"2025-10-21T12:37:12","slug":"klacid-xl-500-mg-14-tablets","status":"publish","type":"product","link":"https:\/\/nawarpharmacy.com\/ru\/product\/klacid-xl-500-mg-14-tablets\/","title":{"rendered":"Klacid XL 500 mg 14 Tablets"},"content":{"rendered":"<p data-start=\"0\" data-end=\"165\"><strong data-start=\"0\" data-end=\"20\">Medication Name:<\/strong> Klacid XL 500 mg Tablets (14 tablets)<br data-start=\"58\" data-end=\"61\" \/><strong data-start=\"61\" data-end=\"83\">Active Ingredient:<\/strong> Clarithromycin 500 mg (extended-release)<br data-start=\"124\" data-end=\"127\" \/><strong data-start=\"127\" data-end=\"142\">Drug Class:<\/strong> Macrolide antibiotic<\/p>\n<hr data-start=\"167\" data-end=\"170\" \/>\n<h3 data-start=\"172\" data-end=\"192\"><strong data-start=\"176\" data-end=\"192\">Indications:<\/strong><\/h3>\n<p data-start=\"193\" data-end=\"279\">Klacid XL 500 mg is used for <strong data-start=\"222\" data-end=\"265\">moderate to severe bacterial infections<\/strong>, including:<\/p>\n<ul data-start=\"280\" data-end=\"497\">\n<li data-start=\"280\" data-end=\"367\">\n<p data-start=\"282\" data-end=\"367\"><strong data-start=\"282\" data-end=\"330\">Upper and lower respiratory tract infections<\/strong> (sinusitis, bronchitis, pneumonia)<\/p>\n<\/li>\n<li data-start=\"368\" data-end=\"407\">\n<p data-start=\"370\" data-end=\"407\"><strong data-start=\"370\" data-end=\"405\">Skin and soft tissue infections<\/strong><\/p>\n<\/li>\n<li data-start=\"408\" data-end=\"497\">\n<p data-start=\"410\" data-end=\"497\"><strong data-start=\"410\" data-end=\"433\">Helicobacter pylori<\/strong> infection (as part of combination therapy for gastric ulcers)<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"499\" data-end=\"502\" \/>\n<h3 data-start=\"504\" data-end=\"532\"><strong data-start=\"508\" data-end=\"532\">Mechanism of Action:<\/strong><\/h3>\n<ul data-start=\"533\" data-end=\"820\">\n<li data-start=\"533\" data-end=\"636\">\n<p data-start=\"535\" data-end=\"636\">Clarithromycin binds to the <strong data-start=\"563\" data-end=\"578\">50S subunit<\/strong> of bacterial ribosomes, blocking <strong data-start=\"612\" data-end=\"633\">protein synthesis<\/strong>.<\/p>\n<\/li>\n<li data-start=\"637\" data-end=\"712\">\n<p data-start=\"639\" data-end=\"712\">This prevents bacterial growth and replication (bacteriostatic action).<\/p>\n<\/li>\n<li data-start=\"713\" data-end=\"820\">\n<p data-start=\"715\" data-end=\"820\">The <strong data-start=\"719\" data-end=\"744\">XL (extended-release)<\/strong> formulation allows <strong data-start=\"764\" data-end=\"785\">once-daily dosing<\/strong> for sustained antibiotic levels.<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"822\" data-end=\"825\" \/>\n<h3 data-start=\"827\" data-end=\"861\"><strong data-start=\"831\" data-end=\"861\">Dosage and Administration:<\/strong><\/h3>\n<ul data-start=\"862\" data-end=\"1183\">\n<li data-start=\"862\" data-end=\"926\">\n<p data-start=\"864\" data-end=\"926\"><strong data-start=\"864\" data-end=\"887\">Typical adult dose:<\/strong> 500 mg <strong data-start=\"895\" data-end=\"909\">once daily<\/strong> for 5\u201314 days.<\/p>\n<\/li>\n<li data-start=\"927\" data-end=\"1018\">\n<p data-start=\"929\" data-end=\"1018\">For severe infections, the dose may be <strong data-start=\"968\" data-end=\"991\">1,000 mg once daily<\/strong> (two 500 mg XL tablets).<\/p>\n<\/li>\n<li data-start=\"1019\" data-end=\"1104\">\n<p data-start=\"1021\" data-end=\"1104\">Take the tablet <strong data-start=\"1037\" data-end=\"1050\">with food<\/strong> and <strong data-start=\"1055\" data-end=\"1072\">swallow whole<\/strong>\u2014do not break, crush, or chew.<\/p>\n<\/li>\n<li data-start=\"1105\" data-end=\"1183\">\n<p data-start=\"1107\" data-end=\"1183\">Complete the <strong data-start=\"1120\" data-end=\"1148\">entire prescribed course<\/strong>, even if symptoms improve early.<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"1185\" data-end=\"1188\" \/>\n<h3 data-start=\"1190\" data-end=\"1211\"><strong data-start=\"1194\" data-end=\"1211\">Side Effects:<\/strong><\/h3>\n<ul data-start=\"1212\" data-end=\"1436\">\n<li data-start=\"1212\" data-end=\"1266\">\n<p data-start=\"1214\" data-end=\"1266\">Common: nausea, vomiting, diarrhea, abdominal pain<\/p>\n<\/li>\n<li data-start=\"1267\" data-end=\"1295\">\n<p data-start=\"1269\" data-end=\"1295\">Metallic or bitter taste<\/p>\n<\/li>\n<li data-start=\"1296\" data-end=\"1331\">\n<p data-start=\"1298\" data-end=\"1331\">Headache, dizziness, or fatigue<\/p>\n<\/li>\n<li data-start=\"1332\" data-end=\"1436\">\n<p data-start=\"1334\" data-end=\"1436\">Rare: rash, liver enzyme elevation, QT prolongation (especially in patients with cardiac conditions)<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"1438\" data-end=\"1441\" \/>\n<h3 data-start=\"1443\" data-end=\"1476\"><strong data-start=\"1447\" data-end=\"1476\">Warnings and Precautions:<\/strong><\/h3>\n<ul data-start=\"1477\" data-end=\"1942\">\n<li data-start=\"1477\" data-end=\"1561\">\n<p data-start=\"1479\" data-end=\"1561\">Do <strong data-start=\"1482\" data-end=\"1493\">not use<\/strong> if allergic to <strong data-start=\"1509\" data-end=\"1523\">macrolides<\/strong> (e.g., erythromycin, azithromycin).<\/p>\n<\/li>\n<li data-start=\"1562\" data-end=\"1631\">\n<p data-start=\"1564\" data-end=\"1631\">Use with caution in patients with <strong data-start=\"1598\" data-end=\"1628\">liver or kidney impairment<\/strong>.<\/p>\n<\/li>\n<li data-start=\"1632\" data-end=\"1860\">\n<p data-start=\"1634\" data-end=\"1657\">Avoid combining with:<\/p>\n<ul data-start=\"1660\" data-end=\"1860\">\n<li data-start=\"1660\" data-end=\"1727\">\n<p data-start=\"1662\" data-end=\"1727\"><strong data-start=\"1662\" data-end=\"1699\">Statins (simvastatin, lovastatin)<\/strong> \u2192 risk of muscle toxicity<\/p>\n<\/li>\n<li data-start=\"1730\" data-end=\"1772\">\n<p data-start=\"1732\" data-end=\"1772\"><strong data-start=\"1732\" data-end=\"1744\">Warfarin<\/strong> \u2192 increased bleeding risk<\/p>\n<\/li>\n<li data-start=\"1775\" data-end=\"1860\">\n<p data-start=\"1777\" data-end=\"1860\"><strong data-start=\"1777\" data-end=\"1834\">Carbamazepine, theophylline, digoxin, ergot alkaloids<\/strong> \u2192 increased drug levels<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li data-start=\"1861\" data-end=\"1942\">\n<p data-start=\"1863\" data-end=\"1942\">May cause <strong data-start=\"1873\" data-end=\"1892\">QT prolongation<\/strong>; avoid in patients with heart rhythm disorders.<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"1944\" data-end=\"1947\" \/>\n<h3 data-start=\"1949\" data-end=\"1965\"><strong data-start=\"1953\" data-end=\"1965\">Storage:<\/strong><\/h3>\n<p data-start=\"1966\" data-end=\"2051\">Store at <strong data-start=\"1975\" data-end=\"2008\">room temperature (below 25\u00b0C)<\/strong>, away from moisture and direct sunlight.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Medication Name: Klacid XL 500 mg Tablets (14 tablets)Active Ingredient: Clarithromycin 500 mg (extended-release)Drug Class: Macrolide antibiotic Indications: Klacid XL 500 mg is used for moderate to severe bacterial infections, including: Upper and lower respiratory tract infections (sinusitis, bronchitis, pneumonia) Skin and soft tissue infections Helicobacter pylori infection (as part of combination therapy for gastric&#8230;<\/p>\n","protected":false},"featured_media":3670,"comment_status":"open","ping_status":"closed","template":"","meta":{"rs_blank_template":"","rs_page_bg_color":"","slide_template_v7":"","_bst_post_transparent":"default","_bst_post_title":"","_bst_post_layout":"default","_bst_post_sidebar_id":"","_bst_post_content_style":"default","_bst_post_vertical_padding":"default","_bst_post_feature":"","_bst_post_feature_position":"","_bst_post_header":false,"_bst_post_footer":false},"product_brand":[],"product_cat":[75,45],"product_tag":[],"product_brands":[],"class_list":{"0":"post-3611","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-antibiotics-antimicrobials","7":"product_cat-medicines","9":"first","10":"instock","11":"shipping-taxable","12":"purchasable","13":"product-type-simple","14":"entry","15":"content-bg","16":"loop-entry"},"_links":{"self":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product\/3611","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/comments?post=3611"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/media\/3670"}],"wp:attachment":[{"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/media?parent=3611"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_brand?post=3611"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_cat?post=3611"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_tag?post=3611"},{"taxonomy":"product_brands","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/ru\/wp-json\/wp\/v2\/product_brands?post=3611"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}