Ceftriaxone Sandoz 1000mg IM Vial

Medication Name: Ceftriaxone Sandoz 1000mg IM Vial

Active Ingredient:
Ceftriaxone 1000 mg

Pharmacological Class:
Third-generation cephalosporin antibiotic

Indications:
Used for the treatment of a wide range of bacterial infections, including:

• Lower and upper respiratory tract infections (pneumonia, bronchitis)

• Urinary tract infections

• Skin and soft tissue infections

• Bone and joint infections

• Intra-abdominal infections

• Gonorrhea

• Meningitis

• Septicemia and other systemic bacterial infections

Mechanism of Action:
Ceftriaxone acts by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs), leading to bacterial cell lysis and death.

Dosage and Administration:

• Adults: 1–2 g once daily, or divided every 12 hours depending on infection severity.

• Children: 50–75 mg/kg/day (maximum 2 g/day).

• Administered intramuscularly (IM) or intravenously (IV).

• For IM injection, reconstitute with sterile water or 1% lidocaine solution to reduce injection pain.

Precautions:

• Contraindicated in patients with known hypersensitivity to cephalosporins.

• Use cautiously in patients with a history of penicillin allergy.

• Dose adjustment may be needed in renal or hepatic impairment.

• Avoid mixing or administering simultaneously with calcium-containing solutions (especially in neonates).

Possible Side Effects:

• Local pain, tenderness, or swelling at injection site

• Nausea, vomiting, or diarrhea

• Headache or dizziness

• Skin rash or pruritus

• Rare: Hypersensitivity reactions, pseudomembranous colitis, or hematologic changes