{"id":4712,"date":"2025-11-05T11:47:59","date_gmt":"2025-11-05T11:47:59","guid":{"rendered":"https:\/\/nawarpharmacy.com\/?post_type=product&p=4712"},"modified":"2025-11-07T12:48:51","modified_gmt":"2025-11-07T12:48:51","slug":"cosimprel-510mg-15-tablets","status":"publish","type":"product","link":"https:\/\/nawarpharmacy.com\/de\/produkt\/cosimprel-510mg-15-tablets\/","title":{"rendered":"Cosimprel 5\\10mg 15 Tablets"},"content":{"rendered":"
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Medication Name:<\/strong> Cosimprel 5\/10mg 15 Tablets<\/p>\n

Active Ingredients (per tablet):<\/strong><\/p>\n

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    Bisoprolol fumarate 5 mg<\/p>\n<\/li>\n

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    Perindopril arginine 10 mg<\/p>\n<\/li>\n<\/ul>\n

    Pharmacological Class:<\/strong><\/p>\n

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      Bisoprolol: Beta-1 selective adrenergic blocker (Beta-blocker)<\/p>\n<\/li>\n

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      Perindopril: Angiotensin-Converting Enzyme (ACE) inhibitor<\/p>\n<\/li>\n<\/ul>\n

      Dosage Form:<\/strong>
      Tablets \u2014 15 per pack<\/p>\n

      Indications:<\/strong><\/p>\n

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        Treatment of essential hypertension (high blood pressure)<\/strong><\/p>\n<\/li>\n

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        Chronic stable heart failure<\/strong> (in some patients under medical supervision)<\/p>\n<\/li>\n

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        Used when combination therapy with a beta-blocker and ACE inhibitor is appropriate<\/p>\n<\/li>\n<\/ul>\n

        Mechanism of Action:<\/strong><\/p>\n

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          Bisoprolol:<\/strong> Reduces heart rate, myocardial contractility, and cardiac output by blocking beta-1 adrenergic receptors in the heart.<\/p>\n<\/li>\n

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          Perindopril:<\/strong> Inhibits the conversion of angiotensin I to angiotensin II, resulting in vasodilation and reduced blood pressure.<\/p>\n<\/li>\n

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          The combination lowers both heart workload and systemic vascular resistance.<\/p>\n<\/li>\n<\/ul>\n

          Dosage:<\/strong><\/p>\n

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            Typical dose: One tablet once daily<\/strong>, preferably in the morning before breakfast.<\/p>\n<\/li>\n

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            Dose adjustments should be made under medical supervision according to blood pressure and clinical response.<\/p>\n<\/li>\n<\/ul>\n

            Precautions:<\/strong><\/p>\n

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              Regular monitoring of blood pressure, heart rate, renal function, and electrolytes<\/strong> is advised.<\/p>\n<\/li>\n

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              Use with caution in patients with renal impairment, heart failure, or bradycardia (slow heart rate)<\/strong>.<\/p>\n<\/li>\n

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              Contraindicated in pregnancy<\/strong>, breastfeeding<\/strong>, severe hypotension<\/strong>, second- or third-degree AV block<\/strong>, and cardiogenic shock<\/strong>.<\/p>\n<\/li>\n

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              Avoid abrupt discontinuation to prevent rebound hypertension or angina.<\/p>\n<\/li>\n<\/ul>\n

              Common Side Effects:<\/strong><\/p>\n

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                Fatigue or dizziness<\/p>\n<\/li>\n

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                Bradycardia (slow heart rate)<\/p>\n<\/li>\n

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                Hypotension (low blood pressure)<\/p>\n<\/li>\n

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                Cough (due to ACE inhibition)<\/p>\n<\/li>\n

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                Headache<\/p>\n<\/li>\n

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                Gastrointestinal upset<\/p>\n<\/li>\n

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                Cold extremities<\/p>\n<\/li>\n<\/ul>\n

                Note:<\/strong>
                Cosimprel 5\/10mg provides a synergistic antihypertensive effect by combining the vasodilatory properties of perindopril with the heart rate\u2013lowering action of bisoprolol, improving cardiovascular control and patient adherence.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

                <\/div>\n<\/div>\n<\/div>\n<\/article>\n
                <\/div>\n","protected":false},"excerpt":{"rendered":"

                Medication Name: Cosimprel 5\/10mg 15 Tablets Active Ingredients (per tablet): Bisoprolol fumarate 5 mg Perindopril arginine 10 mg Pharmacological Class: Bisoprolol: Beta-1 selective adrenergic blocker (Beta-blocker) Perindopril: Angiotensin-Converting Enzyme (ACE) inhibitor Dosage Form:Tablets \u2014 15 per pack Indications: Treatment of essential hypertension (high blood pressure) Chronic stable heart failure (in some patients under medical supervision)…<\/p>\n","protected":false},"featured_media":4869,"comment_status":"open","ping_status":"closed","template":"","meta":{"rs_blank_template":"","rs_page_bg_color":"","slide_template_v7":"","_bst_post_transparent":"default","_bst_post_title":"","_bst_post_layout":"default","_bst_post_sidebar_id":"","_bst_post_content_style":"default","_bst_post_vertical_padding":"default","_bst_post_feature":"","_bst_post_feature_position":"","_bst_post_header":false,"_bst_post_footer":false},"product_brand":[],"product_cat":[80,45],"product_tag":[],"product_brands":[],"class_list":{"0":"post-4712","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-cardiovascular-blood-pressure","7":"product_cat-medicines","9":"first","10":"instock","11":"shipping-taxable","12":"purchasable","13":"product-type-simple","14":"entry","15":"content-bg","16":"loop-entry"},"_links":{"self":[{"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product\/4712","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/comments?post=4712"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/media\/4869"}],"wp:attachment":[{"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/media?parent=4712"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product_brand?post=4712"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product_cat?post=4712"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product_tag?post=4712"},{"taxonomy":"product_brands","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product_brands?post=4712"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}