{"id":4709,"date":"2025-11-05T11:44:59","date_gmt":"2025-11-05T11:44:59","guid":{"rendered":"https:\/\/nawarpharmacy.com\/?post_type=product&#038;p=4709"},"modified":"2025-11-07T12:55:57","modified_gmt":"2025-11-07T12:55:57","slug":"co-tareg-8012-5mg-14-tablets","status":"publish","type":"product","link":"https:\/\/nawarpharmacy.com\/de\/produkt\/co-tareg-8012-5mg-14-tablets\/","title":{"rendered":"Co-Tareg 80\\12.5mg 14 Tablets"},"content":{"rendered":"<article class=\"text-token-text-primary w-full focus:outline-none [--shadow-height:45px] has-data-writing-block:pointer-events-none has-data-writing-block:-mt-(--shadow-height) has-data-writing-block:pt-(--shadow-height) [&amp;:has([data-writing-block])&gt;*]:pointer-events-auto [content-visibility:auto] supports-[content-visibility:auto]:[contain-intrinsic-size:auto_100lvh] scroll-mt-[calc(var(--header-height)+min(200px,max(70px,20svh)))]\" dir=\"auto\" data-turn-id=\"f4ba56f6-cf49-4b37-8f99-e973186f6a8c\" data-testid=\"conversation-turn-663\" data-scroll-anchor=\"true\" data-turn=\"assistant\">\n<div class=\"text-base my-auto mx-auto pb-10 [--thread-content-margin:--spacing(4)] thread-sm:[--thread-content-margin:--spacing(6)] thread-lg:[--thread-content-margin:--spacing(16)] px-(--thread-content-margin)\">\n<div class=\"[--thread-content-max-width:40rem] thread-lg:[--thread-content-max-width:48rem] mx-auto max-w-(--thread-content-max-width) flex-1 group\/turn-messages focus-visible:outline-hidden relative flex w-full min-w-0 flex-col agent-turn\">\n<div class=\"flex max-w-full flex-col grow\">\n<div class=\"min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal [.text-message+&amp;]:mt-1\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"f4ba56f6-cf49-4b37-8f99-e973186f6a8c\" data-message-model-slug=\"gpt-5\">\n<div class=\"flex w-full flex-col gap-1 empty:hidden first:pt-[1px]\">\n<div class=\"markdown prose dark:prose-invert w-full break-words light markdown-new-styling\">\n<p data-start=\"117\" data-end=\"146\"><strong style=\"letter-spacing: 0.15px\" data-start=\"148\" data-end=\"174\">Pharmacological Class:<\/strong><\/p>\n<ul data-start=\"177\" data-end=\"272\">\n<li data-start=\"177\" data-end=\"229\">\n<p data-start=\"179\" data-end=\"229\">Valsartan: Angiotensin II receptor blocker (ARB)<\/p>\n<\/li>\n<li data-start=\"230\" data-end=\"272\">\n<p data-start=\"232\" data-end=\"272\">Hydrochlorothiazide: Thiazide diuretic<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"274\" data-end=\"316\"><strong data-start=\"274\" data-end=\"290\">Dosage Form:<\/strong><br data-start=\"290\" data-end=\"293\" \/>Tablets \u2014 14 per pack<\/p>\n<p data-start=\"318\" data-end=\"336\"><strong data-start=\"318\" data-end=\"334\">Indications:<\/strong><\/p>\n<ul data-start=\"337\" data-end=\"605\">\n<li data-start=\"337\" data-end=\"480\">\n<p data-start=\"339\" data-end=\"480\">Treatment of <strong data-start=\"352\" data-end=\"400\">essential hypertension (high blood pressure)<\/strong> in patients whose blood pressure is not adequately controlled by monotherapy.<\/p>\n<\/li>\n<li data-start=\"481\" data-end=\"605\">\n<p data-start=\"483\" data-end=\"605\">May be used as <strong data-start=\"498\" data-end=\"522\">substitution therapy<\/strong> for patients already stabilized on valsartan and hydrochlorothiazide separately.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"607\" data-end=\"633\"><strong data-start=\"607\" data-end=\"631\">Mechanism of Action:<\/strong><\/p>\n<ul data-start=\"634\" data-end=\"1079\">\n<li data-start=\"634\" data-end=\"806\">\n<p data-start=\"636\" data-end=\"806\"><strong data-start=\"636\" data-end=\"650\">Valsartan:<\/strong> Blocks the effects of angiotensin II at the AT1 receptor, preventing vasoconstriction and aldosterone secretion, which leads to decreased blood pressure.<\/p>\n<\/li>\n<li data-start=\"807\" data-end=\"978\">\n<p data-start=\"809\" data-end=\"978\"><strong data-start=\"809\" data-end=\"833\">Hydrochlorothiazide:<\/strong> Increases sodium and water excretion by inhibiting sodium reabsorption in the distal renal tubules, reducing plasma volume and blood pressure.<\/p>\n<\/li>\n<li data-start=\"979\" data-end=\"1079\">\n<p data-start=\"981\" data-end=\"1079\">The combination provides <strong data-start=\"1006\" data-end=\"1043\">additive antihypertensive effects<\/strong> through complementary mechanisms.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1081\" data-end=\"1094\"><strong data-start=\"1081\" data-end=\"1092\">Dosage:<\/strong><\/p>\n<ul data-start=\"1095\" data-end=\"1249\">\n<li data-start=\"1095\" data-end=\"1165\">\n<p data-start=\"1097\" data-end=\"1165\">Usual dose: <strong data-start=\"1109\" data-end=\"1134\">One tablet once daily<\/strong>, taken with or without food.<\/p>\n<\/li>\n<li data-start=\"1166\" data-end=\"1249\">\n<p data-start=\"1168\" data-end=\"1249\">Dosage may be adjusted based on blood pressure response and clinical condition.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1251\" data-end=\"1269\"><strong data-start=\"1251\" data-end=\"1267\">Precautions:<\/strong><\/p>\n<ul data-start=\"1270\" data-end=\"1680\">\n<li data-start=\"1270\" data-end=\"1385\">\n<p data-start=\"1272\" data-end=\"1385\">Monitor <strong data-start=\"1280\" data-end=\"1372\">renal function, serum electrolytes (especially potassium and sodium), and blood pressure<\/strong> regularly.<\/p>\n<\/li>\n<li data-start=\"1386\" data-end=\"1481\">\n<p data-start=\"1388\" data-end=\"1481\">Use with caution in patients with <strong data-start=\"1422\" data-end=\"1478\">renal impairment, hepatic disease, diabetes, or gout<\/strong>.<\/p>\n<\/li>\n<li data-start=\"1482\" data-end=\"1575\">\n<p data-start=\"1484\" data-end=\"1575\">Contraindicated in <strong data-start=\"1503\" data-end=\"1516\">pregnancy<\/strong>, <strong data-start=\"1518\" data-end=\"1556\">severe renal or hepatic impairment<\/strong>, and <strong data-start=\"1562\" data-end=\"1572\">anuria<\/strong>.<\/p>\n<\/li>\n<li data-start=\"1576\" data-end=\"1680\">\n<p data-start=\"1578\" data-end=\"1680\">Avoid combining with <strong data-start=\"1599\" data-end=\"1624\">potassium supplements<\/strong> or <strong data-start=\"1628\" data-end=\"1659\">potassium-sparing diuretics<\/strong> unless prescribed.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1682\" data-end=\"1708\"><strong data-start=\"1682\" data-end=\"1706\">Common Side Effects:<\/strong><\/p>\n<ul data-start=\"1709\" data-end=\"1893\">\n<li data-start=\"1709\" data-end=\"1741\">\n<p data-start=\"1711\" data-end=\"1741\">Dizziness or lightheadedness<\/p>\n<\/li>\n<li data-start=\"1742\" data-end=\"1753\">\n<p data-start=\"1744\" data-end=\"1753\">Fatigue<\/p>\n<\/li>\n<li data-start=\"1754\" data-end=\"1769\">\n<p data-start=\"1756\" data-end=\"1769\">Hypotension<\/p>\n<\/li>\n<li data-start=\"1770\" data-end=\"1793\">\n<p data-start=\"1772\" data-end=\"1793\">Increased urination<\/p>\n<\/li>\n<li data-start=\"1794\" data-end=\"1825\">\n<p data-start=\"1796\" data-end=\"1825\">Hypokalemia or hyponatremia<\/p>\n<\/li>\n<li data-start=\"1826\" data-end=\"1863\">\n<p data-start=\"1828\" data-end=\"1863\">Elevated blood urea or creatinine<\/p>\n<\/li>\n<li data-start=\"1864\" data-end=\"1893\">\n<p data-start=\"1866\" data-end=\"1893\">Muscle cramps or weakness<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"z-0 flex min-h-[46px] justify-start\"><\/div>\n<\/div>\n<\/div>\n<\/article>\n<div class=\"pointer-events-none h-px w-px\" aria-hidden=\"true\" data-edge=\"true\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Pharmacological Class: Valsartan: Angiotensin II receptor blocker (ARB) Hydrochlorothiazide: Thiazide diuretic Dosage Form:Tablets \u2014 14 per pack Indications: Treatment of essential hypertension (high blood pressure) in patients whose blood pressure is not adequately controlled by monotherapy. May be used as substitution therapy for patients already stabilized on valsartan and hydrochlorothiazide separately. Mechanism of Action: Valsartan:&#8230;<\/p>\n","protected":false},"featured_media":4876,"comment_status":"open","ping_status":"closed","template":"","meta":{"rs_blank_template":"","rs_page_bg_color":"","slide_template_v7":"","_bst_post_transparent":"default","_bst_post_title":"","_bst_post_layout":"default","_bst_post_sidebar_id":"","_bst_post_content_style":"default","_bst_post_vertical_padding":"default","_bst_post_feature":"","_bst_post_feature_position":"","_bst_post_header":false,"_bst_post_footer":false},"product_brand":[],"product_cat":[80,45],"product_tag":[],"product_brands":[],"class_list":{"0":"post-4709","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-cardiovascular-blood-pressure","7":"product_cat-medicines","9":"first","10":"instock","11":"shipping-taxable","12":"purchasable","13":"product-type-simple","14":"entry","15":"content-bg","16":"loop-entry"},"_links":{"self":[{"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product\/4709","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/comments?post=4709"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/media\/4876"}],"wp:attachment":[{"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/media?parent=4709"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product_brand?post=4709"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product_cat?post=4709"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product_tag?post=4709"},{"taxonomy":"product_brands","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product_brands?post=4709"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}