{"id":4707,"date":"2025-11-05T11:41:13","date_gmt":"2025-11-05T11:41:13","guid":{"rendered":"https:\/\/nawarpharmacy.com\/?post_type=product&#038;p=4707"},"modified":"2025-11-07T13:04:34","modified_gmt":"2025-11-07T13:04:34","slug":"coaprovel-15012-5mg-14-tablets","status":"publish","type":"product","link":"https:\/\/nawarpharmacy.com\/de\/produkt\/coaprovel-15012-5mg-14-tablets\/","title":{"rendered":"Coaprovel 150\\12.5mg 14 Tablets"},"content":{"rendered":"<article class=\"text-token-text-primary w-full focus:outline-none [--shadow-height:45px] has-data-writing-block:pointer-events-none has-data-writing-block:-mt-(--shadow-height) has-data-writing-block:pt-(--shadow-height) [&amp;:has([data-writing-block])&gt;*]:pointer-events-auto [content-visibility:auto] supports-[content-visibility:auto]:[contain-intrinsic-size:auto_100lvh] scroll-mt-[calc(var(--header-height)+min(200px,max(70px,20svh)))]\" dir=\"auto\" data-turn-id=\"ba6c21c5-41be-41ee-9506-d4aa148cfdfd\" data-testid=\"conversation-turn-665\" data-scroll-anchor=\"true\" data-turn=\"assistant\">\n<div class=\"text-base my-auto mx-auto pb-10 [--thread-content-margin:--spacing(4)] thread-sm:[--thread-content-margin:--spacing(6)] thread-lg:[--thread-content-margin:--spacing(16)] px-(--thread-content-margin)\">\n<div class=\"[--thread-content-max-width:40rem] thread-lg:[--thread-content-max-width:48rem] mx-auto max-w-(--thread-content-max-width) flex-1 group\/turn-messages focus-visible:outline-hidden relative flex w-full min-w-0 flex-col agent-turn\">\n<div class=\"flex max-w-full flex-col grow\">\n<div class=\"min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal [.text-message+&amp;]:mt-1\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"ba6c21c5-41be-41ee-9506-d4aa148cfdfd\" data-message-model-slug=\"gpt-5\">\n<div class=\"flex w-full flex-col gap-1 empty:hidden first:pt-[1px]\">\n<div class=\"markdown prose dark:prose-invert w-full break-words light markdown-new-styling\">\n<p data-start=\"0\" data-end=\"54\"><strong data-start=\"0\" data-end=\"20\">Medication Name:<\/strong> Coaprovel 150\/12.5mg 14 Tablets<\/p>\n<p data-start=\"56\" data-end=\"94\"><strong data-start=\"56\" data-end=\"92\">Active Ingredients (per tablet):<\/strong><\/p>\n<ul data-start=\"95\" data-end=\"148\">\n<li data-start=\"95\" data-end=\"116\">\n<p data-start=\"97\" data-end=\"116\">Irbesartan 150 mg<\/p>\n<\/li>\n<li data-start=\"117\" data-end=\"148\">\n<p data-start=\"119\" data-end=\"148\">Hydrochlorothiazide 12.5 mg<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"150\" data-end=\"178\"><strong data-start=\"150\" data-end=\"176\">Pharmacological Class:<\/strong><\/p>\n<ul data-start=\"179\" data-end=\"275\">\n<li data-start=\"179\" data-end=\"232\">\n<p data-start=\"181\" data-end=\"232\">Irbesartan: Angiotensin II receptor blocker (ARB)<\/p>\n<\/li>\n<li data-start=\"233\" data-end=\"275\">\n<p data-start=\"235\" data-end=\"275\">Hydrochlorothiazide: Thiazide diuretic<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"277\" data-end=\"319\"><strong data-start=\"277\" data-end=\"293\">Dosage Form:<\/strong><br data-start=\"293\" data-end=\"296\" \/>Tablets \u2014 14 per pack<\/p>\n<p data-start=\"321\" data-end=\"339\"><strong data-start=\"321\" data-end=\"337\">Indications:<\/strong><\/p>\n<ul data-start=\"340\" data-end=\"550\">\n<li data-start=\"340\" data-end=\"406\">\n<p data-start=\"342\" data-end=\"406\">Treatment of <strong data-start=\"355\" data-end=\"403\">essential hypertension (high blood pressure)<\/strong>.<\/p>\n<\/li>\n<li data-start=\"407\" data-end=\"550\">\n<p data-start=\"409\" data-end=\"550\">Particularly indicated in patients whose blood pressure is not adequately controlled by monotherapy with irbesartan or hydrochlorothiazide.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"552\" data-end=\"578\"><strong data-start=\"552\" data-end=\"576\">Mechanism of Action:<\/strong><\/p>\n<ul data-start=\"579\" data-end=\"1019\">\n<li data-start=\"579\" data-end=\"764\">\n<p data-start=\"581\" data-end=\"764\"><strong data-start=\"581\" data-end=\"596\">Irbesartan:<\/strong> Selectively blocks angiotensin II receptors (AT1 subtype), preventing vasoconstriction and aldosterone release, which reduces blood pressure and vascular resistance.<\/p>\n<\/li>\n<li data-start=\"765\" data-end=\"918\">\n<p data-start=\"767\" data-end=\"918\"><strong data-start=\"767\" data-end=\"791\">Hydrochlorothiazide:<\/strong> Inhibits sodium and chloride reabsorption in the distal tubules of the kidney, promoting diuresis and reducing blood volume.<\/p>\n<\/li>\n<li data-start=\"919\" data-end=\"1019\">\n<p data-start=\"921\" data-end=\"1019\">The combination provides <strong data-start=\"946\" data-end=\"983\">additive antihypertensive effects<\/strong> through complementary mechanisms.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1021\" data-end=\"1034\"><strong data-start=\"1021\" data-end=\"1032\">Dosage:<\/strong><\/p>\n<ul data-start=\"1035\" data-end=\"1262\">\n<li data-start=\"1035\" data-end=\"1099\">\n<p data-start=\"1037\" data-end=\"1099\">Usual dose: <strong data-start=\"1049\" data-end=\"1074\">One tablet once daily<\/strong>, with or without food.<\/p>\n<\/li>\n<li data-start=\"1100\" data-end=\"1262\">\n<p data-start=\"1102\" data-end=\"1262\">Dose may be adjusted depending on blood pressure response; higher strengths (e.g., 300\/12.5mg or 300\/25mg) are available for patients needing greater control.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1264\" data-end=\"1282\"><strong data-start=\"1264\" data-end=\"1280\">Precautions:<\/strong><\/p>\n<ul data-start=\"1283\" data-end=\"1716\">\n<li data-start=\"1283\" data-end=\"1369\">\n<p data-start=\"1285\" data-end=\"1369\">Monitor <strong data-start=\"1293\" data-end=\"1356\">renal function, serum potassium, sodium, and blood pressure<\/strong> regularly.<\/p>\n<\/li>\n<li data-start=\"1370\" data-end=\"1462\">\n<p data-start=\"1372\" data-end=\"1462\">Use with caution in <strong data-start=\"1392\" data-end=\"1459\">renal or hepatic impairment, diabetes, or patients on diuretics<\/strong>.<\/p>\n<\/li>\n<li data-start=\"1463\" data-end=\"1593\">\n<p data-start=\"1465\" data-end=\"1593\">Contraindicated in <strong data-start=\"1484\" data-end=\"1497\">pregnancy<\/strong>, <strong data-start=\"1499\" data-end=\"1523\">severe renal failure<\/strong>, <strong data-start=\"1525\" data-end=\"1535\">anuria<\/strong>, and <strong data-start=\"1541\" data-end=\"1561\">hypersensitivity<\/strong> to sulfonamide-derived drugs.<\/p>\n<\/li>\n<li data-start=\"1594\" data-end=\"1716\">\n<p data-start=\"1596\" data-end=\"1716\">Avoid concomitant use with <strong data-start=\"1623\" data-end=\"1648\">potassium supplements<\/strong> or <strong data-start=\"1652\" data-end=\"1683\">potassium-sparing diuretics<\/strong> unless advised by a physician.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1718\" data-end=\"1744\"><strong data-start=\"1718\" data-end=\"1742\">Common Side Effects:<\/strong><\/p>\n<ul data-start=\"1745\" data-end=\"1937\">\n<li data-start=\"1745\" data-end=\"1794\">\n<p data-start=\"1747\" data-end=\"1794\">Dizziness, especially at treatment initiation<\/p>\n<\/li>\n<li data-start=\"1795\" data-end=\"1806\">\n<p data-start=\"1797\" data-end=\"1806\">Fatigue<\/p>\n<\/li>\n<li data-start=\"1807\" data-end=\"1819\">\n<p data-start=\"1809\" data-end=\"1819\">Headache<\/p>\n<\/li>\n<li data-start=\"1820\" data-end=\"1830\">\n<p data-start=\"1822\" data-end=\"1830\">Nausea<\/p>\n<\/li>\n<li data-start=\"1831\" data-end=\"1860\">\n<p data-start=\"1833\" data-end=\"1860\">Muscle cramps or weakness<\/p>\n<\/li>\n<li data-start=\"1861\" data-end=\"1876\">\n<p data-start=\"1863\" data-end=\"1876\">Hypotension<\/p>\n<\/li>\n<li data-start=\"1877\" data-end=\"1937\">\n<p data-start=\"1879\" data-end=\"1937\">Changes in electrolytes (low potassium or sodium levels)<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1939\" data-end=\"2193\" data-is-last-node=\"\" data-is-only-node=\"\"><strong data-start=\"1939\" data-end=\"1948\">Note:<\/strong><br data-start=\"1948\" data-end=\"1951\" \/>Coaprovel 150\/12.5mg offers effective dual-action blood pressure control by combining <strong data-start=\"2037\" data-end=\"2073\">angiotensin II receptor blockade<\/strong> with <strong data-start=\"2079\" data-end=\"2105\">gentle diuretic action<\/strong>, reducing cardiovascular risk in hypertensive patients who require combination therapy.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"z-0 flex min-h-[46px] justify-start\"><\/div>\n<\/div>\n<\/div>\n<\/article>\n<div class=\"pointer-events-none h-px w-px\" aria-hidden=\"true\" data-edge=\"true\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Medication Name: Coaprovel 150\/12.5mg 14 Tablets Active Ingredients (per tablet): Irbesartan 150 mg Hydrochlorothiazide 12.5 mg Pharmacological Class: Irbesartan: Angiotensin II receptor blocker (ARB) Hydrochlorothiazide: Thiazide diuretic Dosage Form:Tablets \u2014 14 per pack Indications: Treatment of essential hypertension (high blood pressure). Particularly indicated in patients whose blood pressure is not adequately controlled by monotherapy with&#8230;<\/p>\n","protected":false},"featured_media":4879,"comment_status":"open","ping_status":"closed","template":"","meta":{"rs_blank_template":"","rs_page_bg_color":"","slide_template_v7":"","_bst_post_transparent":"default","_bst_post_title":"","_bst_post_layout":"default","_bst_post_sidebar_id":"","_bst_post_content_style":"default","_bst_post_vertical_padding":"default","_bst_post_feature":"","_bst_post_feature_position":"","_bst_post_header":false,"_bst_post_footer":false},"product_brand":[],"product_cat":[80,45],"product_tag":[],"product_brands":[],"class_list":{"0":"post-4707","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-cardiovascular-blood-pressure","7":"product_cat-medicines","9":"first","10":"instock","11":"shipping-taxable","12":"purchasable","13":"product-type-simple","14":"entry","15":"content-bg","16":"loop-entry"},"_links":{"self":[{"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product\/4707","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/comments?post=4707"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/media\/4879"}],"wp:attachment":[{"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/media?parent=4707"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product_brand?post=4707"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product_cat?post=4707"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product_tag?post=4707"},{"taxonomy":"product_brands","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product_brands?post=4707"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}