{"id":3777,"date":"2025-10-23T07:29:17","date_gmt":"2025-10-23T07:29:17","guid":{"rendered":"https:\/\/nawarpharmacy.com\/?post_type=product&#038;p=3777"},"modified":"2025-10-23T11:57:29","modified_gmt":"2025-10-23T11:57:29","slug":"septrin-10-tablets","status":"publish","type":"product","link":"https:\/\/nawarpharmacy.com\/de\/produkt\/septrin-10-tablets\/","title":{"rendered":"Septrin 10 Tablets"},"content":{"rendered":"<p><b>Medication Name:<\/b> Septrin 80 mg\/400 mg Tablets (Co-trimoxazole) (10 Tablets)<\/p>\n<p><b>Active Ingredient:<\/b><\/p>\n<ul>\n<li>Trimethoprim 80 mg<\/li>\n<li>Sulfamethoxazole 400 mg<\/li>\n<\/ul>\n<p><b>Pharmacologic Class:<\/b> Combination antibacterial agent (Sulfonamide and Diaminopyrimidine)<\/p>\n<p><b>Indications:<\/b><\/p>\n<ul>\n<li>Treatment and prophylaxis of <i>Pneumocystis jirovecii Pneumonia<\/i> (PJP).<\/li>\n<li>Upper and lower respiratory tract infections (e.g., acute exacerbation of chronic bronchitis).<\/li>\n<li>Uncomplicated urinary tract and renal infections.<\/li>\n<li>Gastrointestinal tract infections (e.g., Shigellosis, Typhoid fever, traveler\u2019s diarrhea).<\/li>\n<li>Acute otitis media (ear infection).<\/li>\n<li>Skin and soft tissue infections caused by susceptible organisms.<\/li>\n<\/ul>\n<p><b>Dosage and Administration:<\/b><\/p>\n<ul>\n<li><b>Standard Dose (Adults and children over 12 years):<\/b> Typically two tablets (2 tablets of 80\/400 mg) every 12 hours (twice daily).<\/li>\n<li><b>For Severe Infections (e.g., PJP):<\/b> Higher, weight-adjusted doses are used, determined by a physician.<\/li>\n<li><b>Administration:<\/b> May be taken with food or drink to minimize stomach upset. It is important to drink plenty of fluids (water) during treatment.<\/li>\n<li>The full course of treatment must be completed as prescribed, even if symptoms improve early.<\/li>\n<\/ul>\n<p><b>Contraindications:<\/b><\/p>\n<ul>\n<li>Hypersensitivity to trimethoprim, sulfamethoxazole, co-trimoxazole, or any component of the formulation.<\/li>\n<li>Known allergy to sulfonamide medicines (e.g., some thiazide diuretics).<\/li>\n<li>Severe liver or severe kidney problems (when plasma concentrations cannot be monitored).<\/li>\n<li>Documented megaloblastic anemia due to folate deficiency.<\/li>\n<li>Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency.<\/li>\n<li>Infants under 6 weeks of age.<\/li>\n<li>History of drug-induced thrombocytopenia (low platelet count) with previous use.<\/li>\n<\/ul>\n<p><b>Precautions:<\/b><\/p>\n<ul>\n<li><b>Severe Skin Reactions:<\/b> Discontinue immediately if any rash, sore throat, or fever occurs. This may indicate rare but life-threatening conditions like Stevens-Johnson Syndrome (SJS) or Toxic Epidermal Necrolysis (TEN).<\/li>\n<li><b>Hematologic Effects:<\/b> Use with caution, especially in the elderly or in patients with pre-existing folate deficiency or those taking other drugs that affect bone marrow. Regular blood count monitoring may be necessary.<\/li>\n<li><b>Renal Impairment:<\/b> Dose adjustments are required for patients with kidney problems.<\/li>\n<li><b>Hyperkalemia:<\/b> May cause high potassium levels in the blood, particularly in patients with renal failure or those taking potassium-sparing drugs.<\/li>\n<li><b>Folate Deficiency:<\/b> Supplementation with folinic acid may be required during long-term therapy.<\/li>\n<li><b>Photosensitivity:<\/b> Avoid excessive exposure to sunlight or UV radiation during treatment and use sun protection.<\/li>\n<\/ul>\n<p><b>Common Side Effects:<\/b><\/p>\n<ul>\n<li>Nausea, vomiting, diarrhea, or abdominal discomfort.<\/li>\n<li>Headache or dizziness.<\/li>\n<li>Skin rash (usually mild, but requires medical assessment).<\/li>\n<li>Hyperkalemia (high potassium levels).<\/li>\n<li>Oral or vaginal candidiasis (Thrush).<\/li>\n<\/ul>\n<p><b>Serious Side Effects (rare):<\/b><\/p>\n<ul>\n<li>Severe allergic reactions (Anaphylaxis, Angioedema, difficulty breathing).<\/li>\n<li>Fatal skin reactions (SJS, TEN).<\/li>\n<li>Severe blood disorders (Agranulocytosis, Aplastic Anemia).<\/li>\n<li>Liver failure or Cholestatic jaundice.<\/li>\n<li>Aseptic meningitis (headache, stiff neck, fever).<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Medication Name: Septrin 80 mg\/400 mg Tablets (Co-trimoxazole) (10 Tablets) Active Ingredient: Trimethoprim 80 mg Sulfamethoxazole 400 mg Pharmacologic Class: Combination antibacterial agent (Sulfonamide and Diaminopyrimidine) Indications: Treatment and prophylaxis of Pneumocystis jirovecii Pneumonia (PJP). Upper and lower respiratory tract infections (e.g., acute exacerbation of chronic bronchitis). Uncomplicated urinary tract and renal infections. Gastrointestinal tract&#8230;<\/p>\n","protected":false},"featured_media":3849,"comment_status":"open","ping_status":"closed","template":"","meta":{"rs_blank_template":"","rs_page_bg_color":"","slide_template_v7":"","_bst_post_transparent":"default","_bst_post_title":"","_bst_post_layout":"default","_bst_post_sidebar_id":"","_bst_post_content_style":"default","_bst_post_vertical_padding":"default","_bst_post_feature":"","_bst_post_feature_position":"","_bst_post_header":false,"_bst_post_footer":false},"product_brand":[],"product_cat":[75,45],"product_tag":[],"product_brands":[],"class_list":{"0":"post-3777","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-antibiotics-antimicrobials","7":"product_cat-medicines","9":"first","10":"instock","11":"shipping-taxable","12":"purchasable","13":"product-type-simple","14":"entry","15":"content-bg","16":"loop-entry"},"_links":{"self":[{"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product\/3777","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/comments?post=3777"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/media\/3849"}],"wp:attachment":[{"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/media?parent=3777"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product_brand?post=3777"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product_cat?post=3777"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product_tag?post=3777"},{"taxonomy":"product_brands","embeddable":true,"href":"https:\/\/nawarpharmacy.com\/de\/wp-json\/wp\/v2\/product_brands?post=3777"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}