Xithrone 15ml Suspension

Medication Name: Xithrone 200 mg/5 mL Oral Suspension (15 mL bottle)
Active Ingredient: Azithromycin 200 mg per 5 mL
Drug Class: Macrolide antibiotic

Indications:

Xithrone suspension is used to treat bacterial infections caused by susceptible organisms, including:

• Upper and lower respiratory tract infections: pharyngitis, tonsillitis, sinusitis, bronchitis, pneumonia

• Ear infections: otitis media

• Skin and soft tissue infections

• Typhoid fever

• Certain gastrointestinal and genitourinary infections

Mechanism of Action:

• Azithromycin binds to the 50S ribosomal subunit of bacteria.

• It inhibits protein synthesis, stopping bacterial growth and replication (bacteriostatic effect).

• Has a long half-life, allowing once-daily dosing and short treatment duration.

Dosage and Administration:

• Children: 10 mg/kg once daily for 3 days, or as prescribed by the physician.

• Shake the bottle well before each dose.

• Use the provided measuring syringe or spoon for accurate dosing.

• May be taken with or without food, but taking with food can reduce stomach upset.

• Complete the entire prescribed course even if symptoms improve early.

Side Effects:

• Nausea, vomiting, diarrhea, abdominal pain

• Headache or dizziness

• Rare: rash, allergic reaction, elevated liver enzymes, QT prolongation (in patients with heart rhythm disorders)

Warnings and Precautions:

• Do not use if allergic to macrolide antibiotics (azithromycin, erythromycin, clarithromycin).

• Use with caution in patients with liver or kidney impairment.

• Avoid combining with drugs that may prolong the QT interval.

• Not effective for viral infections such as colds or flu.

Storage:

• Store below 25°C before reconstitution.

• After adding water, store at room temperature or in the refrigerator (check label instructions).

• Shake well before each use.

• Discard any remaining suspension after 5–7 days.