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Novonorm 2mg 30 Tablets

EGP92

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Novonorm 2 mg (30 Tablets)

Active Ingredient:

  • Repaglinide 2 mg – Oral antidiabetic agent (meglitinide class)

Therapeutic Class:
Antidiabetic (for type 2 diabetes mellitus)

Indications:

  • Type 2 diabetes mellitus (non–insulin-dependent) in adults, particularly when diet and exercise alone are insufficient to control blood glucose.

  • May be used alone (monotherapy) or in combination with metformin or other oral hypoglycemics.

Dosage and Administration:

  • Initial dose: 0.5–1 mg before each main meal.

  • Maintenance dose: Adjust according to blood glucose response; maximum single dose is 4 mg, maximum daily dose 16 mg.

  • Take within 15–30 minutes before meals.

  • If a meal is skipped, the dose should also be skipped.

Mechanism of Action:

  • Repaglinide stimulates insulin release from pancreatic β-cells by closing ATP-dependent potassium channels.

  • Leads to rapid, short-acting insulin secretion that helps control postprandial (after-meal) blood glucose spikes.

Precautions:

  • Contraindicated in:

    • Type 1 diabetes mellitus

    • Diabetic ketoacidosis

    • Severe liver impairment

  • Use with caution in:

    • Elderly patients

    • Those with hepatic or renal impairment

  • Avoid skipping meals after taking the drug (risk of hypoglycemia).

  • Regular monitoring of blood glucose and HbA1c is recommended.

Possible Side Effects:

  • Hypoglycemia (especially if meal is delayed or missed)

  • Headache, dizziness, nausea

  • Abdominal discomfort or diarrhea

  • Rare: Elevated liver enzymes or allergic rash

Storage:

  • Store below 25°C, protected from moisture and direct sunlight.

  • Keep out of reach of children.

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