Gouryst 500mg 100 Tablets

Gouryst 0.5 mg Tablets

Active Ingredient:
Colchicine 0.5 mg

Drug Class:
Anti-gout agent – Anti-inflammatory

Indications:
• Acute gout attacks
• Prevention of recurrent gout attacks
• Familial Mediterranean fever (FMF)

Dosage:

• Acute gout attack: 1–2 tablets at the first sign of attack, followed by 0.5 mg every 2–3 hours until relief or maximum dose is reached.

• Prevention: 0.5–1 mg once or twice daily as prescribed.
  Dose adjustment is required in renal or hepatic impairment.

Contraindications:
• Hypersensitivity to colchicine
• Severe renal or hepatic impairment
• Serious blood disorders (e.g., bone marrow suppression)
• Concomitant use with strong CYP3A4 or P-glycoprotein inhibitors in patients with renal/hepatic impairment

Precautions:
• Use cautiously in elderly patients
• Monitor for gastrointestinal symptoms and signs of toxicity
• Discontinue if severe diarrhea, vomiting, or muscle weakness occurs
• Periodic blood count monitoring during long-term therapy

Common Side Effects:
• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Rare: myopathy, neuropathy, bone marrow suppression

Storage:
Store below 30°C in a dry place.
Keep out of reach of children.