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Ornidaz 500mg 10 Tablets

EGP53

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Medication Name: Ornidaz 500mg 10 Tablets

Active Ingredient:
Ornidazole 500 mg

Pharmacological Class:
Nitroimidazole antimicrobial agent

Indications:
Used for the treatment and prevention of infections caused by anaerobic bacteria and protozoa, including:

  • Amoebiasis (intestinal and hepatic)

  • Giardiasis

  • Trichomoniasis

  • Bacterial vaginosis

  • Anaerobic infections (abdominal, pelvic, or dental infections)

  • Pre- and postoperative prophylaxis in anaerobic contamination risk surgeries

Mechanism of Action:
Ornidazole enters susceptible organisms and disrupts DNA synthesis, leading to cell death. It is effective against anaerobic bacteria and protozoa.

Dosage:

  • Usual adult dose: 500–1000 mg twice daily, depending on infection type and severity.

  • Duration: typically 5–10 days.

  • For prophylaxis: 500 mg before surgery and continued postoperatively as directed.

  • Take with or after food to reduce gastrointestinal discomfort.

Precautions:

  • Avoid alcohol during treatment and for 48 hours after the last dose (risk of disulfiram-like reaction).

  • Use cautiously in patients with liver impairment or CNS disorders (epilepsy).

  • Not recommended during first trimester of pregnancy unless clearly necessary.

  • Dose adjustment may be required in elderly or those with hepatic dysfunction.

Possible Side Effects:

  • Nausea, vomiting, metallic taste

  • Dizziness or headache

  • Abdominal pain or diarrhea

  • Fatigue or weakness

  • Rare: seizures, peripheral neuropathy with prolonged use

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