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Megamox 625 mg 14 Tablets

EGP143

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Medication Name: Megamox 625mg 14 Tablets

Active Ingredients (per tablet):

  • Amoxicillin (as trihydrate) 500 mg

  • Clavulanic acid (as potassium clavulanate) 125 mg

Pharmacological Class:
Broad-spectrum antibiotic (penicillin group, β-lactamase inhibitor combination)

Dosage Form:
Film-coated tablets — for oral administration

Indications:

  • Upper and lower respiratory tract infections (sinusitis, tonsillitis, bronchitis, pneumonia)

  • Urinary tract infections

  • Skin and soft tissue infections

  • Bone and joint infections

  • Dental and postoperative infections

Mechanism of Action:
Amoxicillin inhibits bacterial cell wall synthesis leading to bacterial death.
Clavulanic acid inhibits β-lactamase enzymes that inactivate amoxicillin, restoring its antibacterial activity against resistant strains.

Dosage and Administration:

  • Adults and children >40 kg: 1 tablet every 12 hours.

  • Preferably taken at the start of a meal to enhance absorption and reduce gastrointestinal discomfort.

  • Duration of treatment: 5–14 days as directed by the physician.

Side Effects:

  • Gastrointestinal upset (nausea, diarrhea, abdominal pain)

  • Headache, dizziness

  • Skin rash or allergic reactions

  • Rare: liver enzyme elevation, jaundice, or hypersensitivity

Precautions:

  • Contraindicated in patients allergic to penicillins or β-lactam antibiotics.

  • Use with caution in hepatic or renal impairment.

  • Discontinue immediately if allergic reaction occurs.

Storage:

  • Store below 25°C in a dry place.

  • Keep tablets in the original blister pack, away from light and moisture.

  • Keep out of reach of children.

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